[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100469730":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":11,"centralContacts":16,"locations":25,"responsibleParty":38,"collaborators":7,"id":41,"slug":7,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":7,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":7,"enrollmentInfo":48,"targetDuration":7,"studyType":51,"phases":7,"briefSummary":52,"conditions":53,"keywords":58,"overallStatus":27,"whyStopped":7,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Abramson Cancer Center at Penn Medicine","OTHER",null,[9],{"type":6,"name":10,"description":10,"armGroupLabels":7,"otherNames":7},"Collection of personal health information from women treated at the University of Pennsylvania under an approved HIPAA waiver.",[12],{"name":13,"affiliation":14,"role":15},"Jennifer Zhang, MD","Abramson Cancer Center","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":7,"email":21},"Julia T. Lewandowski","CONTACT","215-662-2861","Julia.Lewandowski@Pennmedicine.upenn.edu",{"name":13,"role":19,"phone":23,"phoneExt":7,"email":24},"215-615-6810","Jennifer.Zhang@Pennmedicine.upenn.edu",[26],{"facility":14,"status":27,"city":28,"state":29,"zip":30,"country":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":7},"RECRUITING","Philadelphia","Pennsylvania","19104","United States",{"type":33,"coordinates":34},"Point",[35,36],-75.16362,39.95238,{"lat":36,"lon":35},{"type":15,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Jennifer Zhang","Assistant Professor of Surgery","100469730",false,"NCT05396612","Role of the Immune Environment in Response to Therapy in Breast Cancer","Inclusion criteria:\n\nWomen 18 years of age or older with non-metastatic breast cancer undergoing surgical resection in the University of Pennsylvania Health System.\n\nExclusion criteria:\n\nMales Children Pregnant individuals","FEMALE","18 Years",{"count":49,"type":50},300,"ESTIMATED","OBSERVATIONAL","This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.",[54,55,56,57],"Breast Cancer","ER Positive Breast Cancer","HER2-negative Breast Cancer","TNBC - Triple-Negative Breast Cancer",[59],"Immune microenvironment","2025-07-02",{"date":62,"type":63},"2025-07-08","ACTUAL",{"date":65,"type":63},"2022-10-03",{"date":67,"type":50},"2032-12-31",{"name":5,"class":6},1]