Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorBettina Mittendorfer

About this trial

The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases, nutrition, and metabolism (the process by which a substance is handled in the body) at the University of Missouri. As technology changes and uses new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure the results are accurate. Reproducibility means performing the same test more than once to see if the same results can be achieved each time. This study will look at the validation and reproducibility of tests and laboratory assays in participants who are healthy or affected by relevant endocrine, cardiometabolic, and musculoskeletal disorders.

Eligibility criteria

Qualifiers

≥18 and ≤100 years of age

body mass index ≥16.0 and ≤60 kg/m2

Disqualifiers

<18 and >100 years of age

body mass index <16.0 or >60 kg/m2

allergies, intolerances, or dietary restrictions to meal ingredients, vegans or vegetarians

use of medications or dietary supplements (e.g., anti-inflammatories, immune modulators, etc) that could interfere with the particular assay/techniques being evaluated

Trial design

Treatments tested in this trial

  • Endothelial cell collection

Treatment groups

No treatment groups listed

Locations

1
University of Missouri-Columbia65211, ColumbiaMissouri, United States

Sponsors and collaborators

Bettina Mittendorfer

Lead sponsor

University of Missouri-Columbia

Sponsor institution