rTMS Efficacy Coupled With Mirror Therapy
ConditionNeuropathic Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorCentre Hospitalier Universitaire de Saint Etienne
About this trial
Neuropathic pain is particularly difficult to treat with classic first-line drugs. Neuromodulation techniques using repetitive transcranial magnetic stimulation (rTMS) are useful alternative, but there is a need to improve their analgesic effect.Virtual reality mirror therapy has shown the capacity to alleviate pain and may be easily coupled with rTMS.The present project will investigate in individuals with neuropathic pain the effects of the rTMS coupled with virtual reality mirror therapy.
Eligibility criteria
Qualifiers
Clinical symptoms typical of neuropathic pain
Refractory to drug therapies
Lasting for at least 6 months, with a moderate to severe pain intensity (≥4/10 on Visual Analog Scale, VAS) and a stable pain treatment since 1month at least
Having right to health benefits
Disqualifiers
Ferromagnetic components and implanted microprocessors (i.e. cochlear implants)
Drug-resistant or active epilepsy, pacemaker, pregnancy, ongoing depression or personality troubles, and ongoing opioid treatment.
Any other contraindications to MRI scanner (e.g., claustrophobia, etc.).
Trial design
Treatments tested in this trial
- Repetitive transcranial magnetic stimulation (rTMS)
- Mirror therapy using virtual reality
- Mirror therapy using sham mirror
Treatment groups
64 Participants
are divided into 2 treatment groupsLocations
2Hôpital Neurologique Pierre Wertheimer69500, Bron France
Centre Hospitalier Universitaire de Saint-Etienne42055, Saint-Etienne France
Sponsors and collaborators
Centre Hospitalier Universitaire de Saint Etienne
Lead sponsor
Source ClinicalTrials.gov