[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608742":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":33,"collaborators":7,"id":35,"slug":7,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":7,"eligibilityCriteria":39,"healthyVolunteers":40,"sex":41,"minAge":42,"maxAge":7,"enrollmentInfo":43,"targetDuration":7,"studyType":46,"phases":7,"briefSummary":47,"conditions":48,"keywords":54,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"RenJi Hospital","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"nothing","This is an observational study.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"融 黄, Ph.D","CONTACT","+862168383816","11084@renji.com",[19],{"facility":20,"status":21,"city":22,"state":7,"zip":7,"country":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Department of Geriatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.","RECRUITING","Shanghai","China",{"type":25,"coordinates":26},"Point",[27,28],121.45806,31.22222,{"lat":28,"lon":27},[31],{"name":32,"role":15,"phone":16,"phoneExt":7,"email":17},"Rong Huang, Ph.D",{"type":34,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100608742",false,"NCT07205510","Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)","Inclusion Criteria:\n\nAdults aged 18 and over\n\nExclusion Criteria:\n\n1. Does not cooperate in signing the informed consent form;\n2. Does not possess legal capacity;\n3. In a state of loss of consciousness;\n4. Suffering from severe mental illness, unable to communicate normally;\n5. The researcher believes that the subject has a disease that affects the assessment of results and is unsuitable for inclusion.",true,"ALL","18 Years",{"count":44,"type":45},10000,"ESTIMATED","OBSERVATIONAL","This study aims to establish an ambispective cohort platform centered on the pathological axis of \"sarcopenia-metabolic disorders-aging progression\", integrating multimodal data including demographic characteristics, lifestyle factors, clinical phenotypes, laboratory tests, medical imaging, and biospecimens. Namely 'Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)'.",[49,50,51,52,53],"Sarcopenia","Metabolic Diseases","All-cause Mortality","Aging","Cardiometabolic Diseases",[49,50,52,55,53],"All-cause mortality","2025-09-25",{"date":58,"type":59},"2025-10-03","ACTUAL",{"date":61,"type":59},"2020-12-01",{"date":63,"type":45},"2040-12-31",{"name":5,"class":6},1]