[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492000":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":52,"collaborators":56,"id":60,"slug":10,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":10,"maxAge":10,"enrollmentInfo":67,"targetDuration":70,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Zhujiang Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Multiple myeloma",null,"Multiple myeloma (MM) is a hematologic malignant tumor characterized by abnormally cloned plasma cells in bone marrow, whose growth can lead to destructive bone injury, acute kidney injury, anemia, and hypercalcemia.",[13],"Other: Observational studies, no intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy control","Individuals in good health without obvious disease and with normal physical examination report; Avoid people who have not suffered from major chronic diseases in recent years, such as hypertension, diabetes, chronic kidney disease, etc; controls were appropriately selected that matched cases for age and sex.",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"Observational studies, no intervention",[15,9],[23],{"name":24,"affiliation":5,"role":25},"Hongwei Zhou, Professor","STUDY_CHAIR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Nianyi Zeng","CONTACT","13928801657","+86","zengny1@i.smu.edu.cn",{"name":24,"role":29,"phone":34,"phoneExt":31,"email":35},"18688489622","hzhou@smu.edu.cn",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Zhujiang Hospital of Southern Medical University","RECRUITING","Guangzhou","Guangdong","510000","China",{"type":45,"coordinates":46},"Point",[47,48],113.25,23.11667,{"lat":48,"lon":47},[51],{"name":24,"role":29,"phone":34,"phoneExt":10,"email":35},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hongwei Zhou","Professor",[57],{"name":58,"class":59},"National Natural Science Foundation of China","OTHER_GOV","100492000",false,"NCT05686447","Screening and Therapeutic Monitoring of Multiple Myeloma by MALDI-TOF MS Analysis","Inclusion Criteria:(1) Inclusion criteria for cases: Serum samples from related people diagnosed with multiple myeloma were included in MALDI-TOF-MS analysis by serum protein electrophoresis (SPEP), serum immunofixation electrophoresis (IFE), Ig isotype detection and other methods. (2) Inclusion criteria of the controls were as follows: individuals in good health without obvious disease and with normal physical examination report; Avoid people who have not suffered from major chronic diseases in recent years, such as hypertension, diabetes, chronic kidney disease, etc; controls were appropriately selected that matched cases for age and sex.\n\n\\-\n\nExclusion Criteria: samples with incomplete sample information and untraceable source; Samples whose sample volume is insufficient for testing; Samples that do not meet the requirements for sample collection and storage\n\n\\-",true,"ALL",{"count":68,"type":69},200,"ESTIMATED","2 Years","OBSERVATIONAL","To provide a comprehensive MALDI-TOF mass spectrometry method for detecting, characterizing, and quantifying M-protein, and to track M-protein in a very sensitive and specific manner during patient treatment, providing a more precise test for diagnosing disease and monitoring patient response to treatment.",[74,75,76],"Monoclonal Gammopathies","Multiple Myeloma","M-protein",[76],"2025-04-02",{"date":80,"type":81},"2025-04-06","ACTUAL",{"date":83,"type":81},"2023-01-01",{"date":85,"type":69},"2026-07-31",{"name":5,"class":6},1]