[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100540310":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":62,"collaborators":65,"id":69,"slug":10,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":82,"studyType":83,"phases":10,"briefSummary":84,"conditions":85,"keywords":98,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Seattle Children's Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Inflammatory Bowel Disease",null,"Participants will enroll before their initial diagnostic procedure. After pathology results are reported, participants will be categorized based on the assigned diagnoses: Inflammatory Bowel Disease (IBD) \\[Crohn's disease (CD), ulcerative colitis (UC), and Indeterminate Colitis (IC)\\] vs Disorders of the Brain-Gut Interactions (DGBI).\n\nParticipation in the IBD cohort will last for three years.",[13,14],"Diagnostic Test: Esophagogastroduodenoscopy (EGD) with biopsy","Diagnostic Test: Colonoscopy w\u002F biopsy",{"label":16,"type":10,"description":17,"interventionNames":18},"Disorders of the Brain-Gut Interactions","Participants will enroll before their initial diagnostic procedure. After pathology results are reported, participants will be categorized based on the assigned diagnoses: Inflammatory Bowel Disease (IBD) \\[Crohn's disease (CD), ulcerative colitis (UC), and Indeterminate Colitis (IC)\\] vs Disorders of the Brain-Gut Interactions (DGBI).\n\n-The DGBI cohort will be subdivided into: Esophageal Disorder, Gastroduodenal Disorder, Bowel Disorder, Centrally Mediated Disorders of GI Pain, Gallbladder and Sphincter of Oddi Disorder, Anorectal Disorder, Childhood Functional GI Disorders: Neonate\u002FToddler, Childhood Functional GI Disorders: Child\u002FAdolescent\n\nParticipation in the DGBI cohort will include the initial sample and data collection as well an one further medical record extraction at month 24.",[13,14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"DIAGNOSTIC_TEST","Esophagogastroduodenoscopy (EGD) with biopsy","Esophagogastroduodenoscopy (EGD) is a test procedure to examine the lining of the esophagus, stomach, and first part of the small intestine.",[16,9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Colonoscopy w\u002F biopsy","Colonoscopy is a test procedure to examine the lining of the different portions of the large intestine: cecum, colon, rectum, and anal canal.",[16,9],[30],{"name":31,"affiliation":32,"role":33},"Betty (Hengqi) Zheng, MD","Seattle Children's Hospital, University of Washington","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Mason E Nuding, BS","CONTACT","206-987-0055","mason.nuding@seattlechildrens.org",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Seattle","Washington","98105","United States",{"type":48,"coordinates":49},"Point",[50,51],-122.33207,47.60621,{"lat":51,"lon":50},[54,56,60],{"name":55,"role":37,"phone":38,"phoneExt":10,"email":39},"Mason E Nuding",{"name":57,"role":37,"phone":58,"phoneExt":10,"email":59},"Clinical Research Coordinator","206-987-2521","giresearch@seattlechidlrens.org",{"name":61,"role":33,"phone":10,"phoneExt":10,"email":10},"Hengqi Zheng, MD",{"type":33,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Betty Zheng","Assistant Professor, Director of Advanced IBD Fellowship Program",[66],{"name":67,"class":68},"Allen Institute","UNKNOWN","100540310",false,"NCT06315179","Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)","Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation","STRIDE","Inclusion Criteria:\n\n* Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)\n\nExclusion Criteria:\n\n* Evidence of Other Complicating Medical Issues:\n* Other serious medical conditions, such as neurological, liver, kidney, or systemic disease\n* Pregnancy\n* Tobacco, alcohol, or illicit drug abuse","ALL","6 Years","21 Years",{"count":80,"type":81},200,"ESTIMATED","3 Years","OBSERVATIONAL","This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.",[86,87,88,89,90,91,92,93,94,95,96,97],"Inflammatory Bowel Diseases","Crohn Disease","Ulcerative Colitis","Indeterminate Colitis","Functional Abdominal Pain Syndrome","Functional Bowel Disorder","Esophageal Diseases","Gastroduodenal Disorder","Bowel Dysfunction","Gallbladder Diseases","Sphincter of Oddi Dysfunction","Anorectal Disorder",[99,100],"IBD","DGBI","2026-04-21",{"date":103,"type":104},"2026-04-24","ACTUAL",{"date":106,"type":104},"2024-05-10",{"date":108,"type":81},"2030-01",{"name":5,"class":6},1]