Health Trials

About this trial

The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications.

The objectives are to:

1. Derive and externally validate a new highly sensitive and maximally specific clinical decision rule for the exclusion of traumatic brain injury in head-injured ED patients who take anticoagulant medications; and, 2. Estimate the sensitivity and specificity of existing head injury clinical decision rules in head-injured ED patients who take anticoagulant medications.

Eligibility criteria

Qualifiers

Age ≥16 years

Presents to the emergency department after a head injury

Patient has a head CT in the emergency department

Is a current anticoagulant user

Disqualifiers

Head injury occurred >48 h before patient's arrival to the emergency department

Penetrating head injury

Previously enrolled

Patient resides outside of the hospital's catchment area

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Locations

7
University of British ColumbiaV6T 1Z4, VancouverBritish Columbia, Canada
Hamilton Health Sciences CorporationL8L 2X2, HamiltonOntario, Canada
Kingston Health Sciences CentreN3T 6P9, KingstonOntario, Canada
Ottawa Hospital Research InstituteK1H 8L6, OttawaOntario, Canada

Sponsors and collaborators

Dr. Kerstin de Wit

Lead sponsor

Queen's University

Sponsor institution

Canadian Institutes of Health Research (CIHR)

Collaborator

Source ClinicalTrials.gov