[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548748":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":43,"locations":52,"responsibleParty":93,"collaborators":96,"id":101,"slug":30,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":102,"sex":108,"minAge":109,"maxAge":30,"enrollmentInfo":110,"targetDuration":30,"studyType":113,"phases":114,"briefSummary":116,"conditions":117,"keywords":121,"overallStatus":78,"whyStopped":30,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"Dartmouth-Hitchcock Medical Center","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Music Piece A","EXPERIMENTAL","Participants will be asked to listen to a musical excerpt previously shown to have a positive effect on epileptic activity in human brain.",[13],"Other: Experimental Intervention (Music A)",{"label":15,"type":16,"description":17,"interventionNames":18},"Music Piece B","ACTIVE_COMPARATOR","Participants will be asked to listen to a musical except very similar to the experimental stimuli that has not been shown to have a positive effect on epileptic activity.",[19],"Other: Active Comparator Intervention (Music B)",{"label":21,"type":16,"description":22,"interventionNames":23},"Music Piece C","Participants will select a preferred excerpt from several popular musical genres. This piece is modified to have some similarities to the experimental musical excerpt.",[24],"Other: Active Comparator Intervention (Music C)",[26,31,35],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Experimental Intervention (Music A)","Participants will be asked to listen to Music A on their personal device daily, at a time most convenient for them.",[9],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Active Comparator Intervention (Music B)","Participants will be asked to listen to music B on their personal device daily, at a time most convenient for them.",[15],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Active Comparator Intervention (Music C)","Participants will be asked to listen to music C on their personal device daily, at a time most convenient for them.",[21],[40],{"name":41,"affiliation":5,"role":42},"Brian C Fidali, MD","PRINCIPAL_INVESTIGATOR",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":30,"email":48},"Anastasia Kanishcheva, MPH","CONTACT","603-650-0260","Anastasia.Kanishcheva@Hitchcock.ORG",{"name":41,"role":46,"phone":50,"phoneExt":30,"email":51},"603-650-5104","Brian.C.Fidali@hitchcock.org",[53,77],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"University of Massachusetts Chan Medical School","NOT_YET_RECRUITING","Worcester","Massachusetts","01655","United States",{"type":61,"coordinates":62},"Point",[63,64],-71.80229,42.26259,{"lat":64,"lon":63},[67,70,73,76],{"name":68,"role":46,"phone":30,"phoneExt":30,"email":69},"CJ Hill","Charles.hill6@umassmed.edu",{"name":71,"role":46,"phone":30,"phoneExt":30,"email":72},"Natalie Erlich-Malona, MD","Natalie.Erlich-Malona@umassmemorial.org",{"name":74,"role":75,"phone":30,"phoneExt":30,"email":30},"Felicia Chu, MD","SUB_INVESTIGATOR",{"name":71,"role":42,"phone":30,"phoneExt":30,"email":30},{"facility":5,"status":78,"city":79,"state":80,"zip":81,"country":59,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"RECRUITING","Lebanon","New Hampshire","03756",{"type":61,"coordinates":83},[84,85],-72.25176,43.64229,{"lat":85,"lon":84},[88,89,90,91],{"name":45,"role":46,"phone":47,"phoneExt":30,"email":48},{"name":41,"role":46,"phone":50,"phoneExt":30,"email":51},{"name":41,"role":42,"phone":30,"phoneExt":30,"email":30},{"name":92,"role":75,"phone":30,"phoneExt":30,"email":30},"Barbara C Jobst, MD",{"type":42,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Brian Fidali, MD","Principal Investigator",[97,99],{"name":98,"class":6},"Dartmouth College",{"name":100,"class":6},"University of Massachusetts, Worcester","100548748",false,"NCT06425029","Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application","SONATA: Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application","SONATA","Inclusion Criteria:\n\n* Adults with medication-refractory focal epilepsy who have undergone RNS implantation at least six months prior and are in the judgement of the treating physician on a stable RNS regimen in terms of stimulation\n* Willing to attend all study visits and complete all required study procedures\n* Access to private or public wireless data service at regular intervals\n* Access to personal mobile device\n\nExclusion Criteria:\n\n* Documentation of a musicogenic, or auditory-triggered focal seizure semiology\n* Participant is unable to reasonably participate in study tasks as determined by the investigator\n* Inability to obtain informed consent from the patient or legally authorized representative","ALL","18 Years",{"count":111,"type":112},24,"ESTIMATED","INTERVENTIONAL",[115],"NA","This is a prospective, placebo-controlled, double-blinded randomized study of self-administered auditory intervention in a naturalistic home environment.",[118,119,120],"Epilepsy","Refractory Epilepsy","Music",[122,123,124,125],"music","epilepsy","responsive neurostimulation","interictal discharge","2026-05-18",{"date":128,"type":129},"2026-05-20","ACTUAL",{"date":131,"type":129},"2025-07-22",{"date":133,"type":112},"2027-12",{"name":5,"class":6},2]