[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436000":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":28,"locations":33,"responsibleParty":49,"collaborators":23,"id":51,"slug":23,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":23,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":36,"whyStopped":23,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University Hospital, Toulouse","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"6 weeks phase A","According to SCED methodology design :\n\nPhase A, which constitutes the control period of semantic therapy, will be composed of lexico-phonological training exercises (Piroux-Davous, 2018). This phase will last 6 weeks (i.e. 18 sessions), at the rate of 3 speech therapy sessions of 45 minutes per week.",[12],"Behavioral: semantic therapy and semantic re-education",{"label":14,"type":6,"description":15,"interventionNames":16},"8 weeks phase A","According to SCED methodology design :\n\nPhase A, which constitutes the control period of semantic therapy, will be composed of lexico-phonological training exercises (Piroux-Davous, 2018). This phase will last 8 weeks (i.e. 24 sessions), at the rate of 3 speech therapy sessions of 45 minutes per week.",[12],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL","semantic therapy and semantic re-education","Patients will be followed over two periods \"Phase A (randomized, 6 to 8 weeks) - Phase B (5 weeks)\".\n\nPhase A : Baseline Phase A, which constitutes the control period of semantic therapy, will be composed of lexico-phonological training exercises (Piroux-Davous, 2018). This phase will last 6 to 8 weeks (i.e. 18 to 24 sessions) depending on the randomisation, at the rate of 3 speech therapy sessions of 45 minutes per week.\n\nPhase B : Semantic re-education The sessions will consist of training based on the analysis of semantic traits (Coustaut, 2019). This phase will last 5 weeks (i.e. 15 sessions), at the rate of 3 speech therapy sessions of 45 minutes per week.\n\nIn accordance with the application of the SCED methodology, repeated measurements will be carried out every second session during phases A and B. They will consist of proposing the oral naming task (lasting 10 minutes).",[9,14],null,[25],{"name":26,"affiliation":5,"role":27},"Jérémie PARIENTE, MD PhD","PRINCIPAL_INVESTIGATOR",[29],{"name":26,"role":30,"phone":31,"phoneExt":23,"email":32},"CONTACT","0561777686","pariente.j@chu-toulouse.fr",[34],{"facility":35,"status":36,"city":37,"state":23,"zip":23,"country":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"CHU Toulouse","RECRUITING","Toulouse","France",{"type":40,"coordinates":41},"Point",[42,43],1.44367,43.60426,{"lat":43,"lon":42},[46],{"name":47,"role":30,"phone":48,"phoneExt":23,"email":32},"Jérémie Pariente, MD, PhD","05.61.77.95.02",{"type":50,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100436000",false,"NCT04957537","Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia","Evaluation of the Effect of a Semantic Rehabilitation in Patients in the Mild to Moderate Stage of Primary Progressive Semantic Aphasia : a SCED Study","SCED-APPvs","Inclusion Criteria:\n\n* Have a diagnosis of primary progressive semantic aphasia according to the criteria of Gorno-Tempini et al (2011) (Appendix A)\n* Being in the mild to moderate stage of dementia (MMSE score between 10 and 28) (Crum et al., 1993; Derouesné et al., 1999)\n* Common French\n* Being affiliated to a social security scheme\n* Being over the age of 18 years old\n\nExclusion Criteria:\n\n* Have significant uncorrected visual and\u002For hearing impairment\n* Have a history of brain injuries, major head trauma\n* Have untreated psychiatric disorders\n* Have significant motor and\u002For comprehension problems that make it impossible to take part in the study\n* Chronical use of drugs and\u002For alcohol\n* Under guardians or curators\n* Severe depression (Beck's depression scale score \\> 9) (Beck \\& al., 1961)","ALL","18 Years","100 Years",{"count":62,"type":63},15,"ESTIMATED","INTERVENTIONAL",[66],"NA","This project aims to measure the effect of a semantic rehabilitation protocol for patients with primary progressive semantic aphasia and using the SCED methodology.",[69],"Primary Progressive Aphasia",[71,72,73,74,75,76,77,78,79],"Semantic primary progressive aphasia","semantic variant (svPPA)","speech therapy","anomia","metacognition","Single Case Experimental Design","technology","naming","speed of lexical access","2024-08-01",{"date":82,"type":83},"2024-08-02","ACTUAL",{"date":85,"type":83},"2021-09-20",{"date":87,"type":63},"2025-09",{"name":5,"class":6},1]