[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580876":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":63,"collaborators":26,"id":67,"slug":26,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":26,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Jinling Hospital, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CCTA-based follow-up management group","ACTIVE_COMPARATOR","The subjects will undergo routine clinical and laboratory examinations, as well as follow-up CCTA examinations to assess the progression of plaques and to recommend appropriate management, treatment, and follow-up based on the findings",[13],"Diagnostic Test: Coronary Computed Tomography Angiography",{"label":15,"type":16,"description":17,"interventionNames":18},"clinical-based follow-up management group","SHAM_COMPARATOR","The subjects will undergo routine clinical and laboratory examinations, and recommendations for appropriate management, treatment, and follow-up will be made based on the results.",[19],"Other: Current clinical guidelines",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIAGNOSTIC_TEST","Coronary Computed Tomography Angiography","Based on the assessment of plaque progression after follow-up CCTA examination, patients will be given either intensive treatment or routine treatment.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Current clinical guidelines","Patients will be treated according to the 2024 ESC Guidelines for the Management of Chronic Coronary Syndromes.",[15],[32],{"name":33,"affiliation":34,"role":35},"Trail Manager","Jinling Hospital,Nanjing University School of Medicine,Nanjing,China","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Longjiang Zhang, MD","CONTACT","13405833167","kevinzhlj@163.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Research Institute Of Medical Imaging Jinling Hospital","RECRUITING","Nanjing","Jiangsu","210018","China",{"type":51,"coordinates":52},"Point",[53,54],118.77778,32.06167,{"lat":54,"lon":53},[57,59],{"name":38,"role":39,"phone":58,"phoneExt":26,"email":41},"13405833176",{"name":60,"role":39,"phone":61,"phoneExt":26,"email":62},"Chao Li, MD","18822060230","lclive123123@163.com",{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Zhang longjiang,MD","Principal Investigator : Zhang longjiang","100580876",false,"NCT06843005","Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease","Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease: a Randomised Controlled Trial","SUCCESS","Inclusion Criteria:\n\n1. Age between 18 and 80 years old;\n2. Known patients with non-obstructive coronary artery disease (disease duration ≥2 years);\n3. Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations.\n\nExclusion Criteria:\n\n1. Patients who have experienced ACS or PCI\u002FCABG;\n2. Patients who have experienced adverse cardiovascular and cerebrovascular events;\n3. Patients who have undergone follow-up CCTA or DSA examinations before enrollment;\n4. Patients with severe hepatic and renal dysfunction;\n5. Patients with contraindications to CCTA examinations;\n6. Patients with poor initial CCTA image quality or data loss.","ALL","18 Years","80 Years",{"count":78,"type":79},3100,"ESTIMATED","INTERVENTIONAL",[82],"NA","The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.",[85,86,87,88],"Major Adverse Cardiovascular Events (MACE)","Prevention","Coronary Artery Disease(CAD)","CT Angiography","2026-03-19",{"date":91,"type":92},"2026-03-24","ACTUAL",{"date":94,"type":92},"2025-02-28",{"date":96,"type":79},"2028-12-30",{"name":65,"class":6},1]