Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorM.D. Anderson Cancer Center

About this trial

To learn how radiation treatment may affect your responses to vaccines against pneumonia.

Eligibility criteria

Qualifiers

Group 1A

Group 1B

Group 2A

Group 2B

Disqualifiers

Patients with compromised immunologic responses due to an uncontrolled intercurrent immunodeficiency (e.g., Human immunodeficiency virus (HIV), X-linked agammaglobulinemia) or previous or current immune suppressive therapy

Patients receiving intravenous immunoglobulin (IVIG) during the study or in the three months prior to study enrollment.

Patients with psychiatric illness/social situations that would limit compliance with study requirements.

Individuals with previous pneumococcal vaccination in the last 5 years.

Trial design

Treatments tested in this trial

  • Pneumonia vaccine

Treatment groups

80 Participants
are divided into 3 treatment groups

Locations

1
MD Anderson Cancer Center77030, HoustonTexas, United States

Sponsors and collaborators

M.D. Anderson Cancer Center

Lead sponsor