[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436153":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":20,"locations":25,"responsibleParty":45,"collaborators":20,"id":48,"slug":20,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":20,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":20,"enrollmentInfo":57,"targetDuration":20,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":28,"whyStopped":20,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Respiratory Function Testing","EXPERIMENTAL","All subjects will receive standard respiratory function testing and ultrasound-based elastography measurements across various behaviors and conditions",[13],"Diagnostic Test: Shear-wave elastography",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Shear-wave elastography","Ultrasound based imaging of diaphragm muscle activity",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Carlos Matilla, MD, PhD","PRINCIPAL_INVESTIGATOR",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Mayo Clinic in Rochester","RECRUITING","Rochester","Minnesota","55905","United States",{"type":34,"coordinates":35},"Point",[36,37],-92.4699,44.02163,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":43,"phoneExt":20,"email":44},"Carlos B Mantilla","CONTACT","507-255-1612","mantilla.carlos@mayo.edu",{"type":24,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Carlos B Mantilla, MD, PhD","Principal Investigator","100436153",false,"NCT04959526","Shear-wave Elastography Compared to Respiratory Function Testing","Comparison of Shear-wave Elastography to State-of-the-art Respiratory Function Testing to Measure the Range of Forces Generated by the Diaphragm Muscle","Inclusion Criteria:\n\n\\- Adult male and female healthy volunteers.\n\nExclusion Criteria:\n\n* Volunteers who are pregnant.\n* Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).",true,"ALL","18 Years",{"count":58,"type":59},24,"ESTIMATED","INTERVENTIONAL",[62],"NA","The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.",[65,66],"Respiratory Function Loss","Respiratory Complication",[68,69],"Elastography","Ultrasound","2026-03-12",{"date":72,"type":73},"2026-03-16","ACTUAL",{"date":75,"type":73},"2021-07-28",{"date":77,"type":59},"2026-12",{"name":5,"class":6},1]