About this trial
The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS dependency in patients suffering from an aneurysmal subarachnoid haemorrhage (aSAH). The main questions we aim to answer are:
* Is there an association of glucose levels on VPS dependency in patients requiring extra-ventricular-drain (EVD) placement for aSAH? * In addition, if there is, what is the influence the course of glucose levels has on VPS dependency?
Glucose levels in CSF and serum will be measured on admission, or in case of CSF, upon EVD placement. Glucose in CSF will then be measured every day until EVD removal together with serum glucose. Follow-up will be conducted in person after 3 and 6 months.
Eligibility criteria
Qualifiers
18 years old and older
Hospital admission due to an aneurysmal subarachnoid haemorrhage (radiological confirmation needed)
Disqualifiers
Younger than 18 years old
Non-aneurysmal subarachnoid haemorrhage (eg. trauma, perimesencephalic subarachnoid haemorrhage, mycotic or flow-associated aneurysms)
Previous enrolment into the current study
Trial design
Treatments tested in this trial
- Cerebrospinal Fluid (CSF) Sample
- Blood Serum Sample
Treatment groups
Locations
3Sponsors and collaborators
Isabel Hostettler
Lead sponsor
Cantonal Hospital of St. Gallen
Sponsor institution
Kantonsspital Aarau
Collaborator
University Hospital, Basel, Switzerland
Collaborator