[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584218":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":51,"collaborators":24,"id":53,"slug":24,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":24,"enrollmentInfo":62,"targetDuration":24,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":37,"whyStopped":24,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of Illinois at Chicago","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Mediterranean Diet","EXPERIMENTAL","Commercially prepared foods will be provided.",[13,14],"Other: Mediterranean Diet","Other: Usual Diet",{"label":16,"type":17,"description":18,"interventionNames":19},"Usual Diet","ACTIVE_COMPARATOR","Consume their typical at-home diet.",[13,14],[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Mediterranean Diet foods will be provided for 4 weeks.",[9,16],null,{"type":6,"name":16,"description":26,"armGroupLabels":27,"otherNames":24},"Participants will consume their typical at home-diet.",[9,16],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Lisa Tussing-Humphreys, PhD, MS, RD","CONTACT","312-355-5521","tussing@uic.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"University of Illinois Chicago","RECRUITING","Chicago","Illinois","60612","United States",{"type":43,"coordinates":44},"Point",[45,46],-87.65005,41.85003,{"lat":46,"lon":45},[49],{"name":50,"role":31,"phone":32,"phoneExt":24,"email":33},"Lisa Tussing-Humphreys, PhD, MS, RDN",{"type":52,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100584218",false,"NCT06886477","Sickle Cell, Pain and Mediterranean Diet","Exploring the Mediterranean Diet as A Promising Approach for Alleviating Chronic Pain in Sickle Cell Disease","MedSCP","Inclusion Criteria:\n\n* Sickle Cell Disease Diagnosis\n* Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for \\> 6 months (based on a response of \"Most days,\" \"Every day,\" or \"Some days\" and not \"Never\" to the question \"In the past 6 months, how often have you had pain?\")\n* Ability to speak, read, write, and understand English\n* A Mediterranean Eating Pattern for Americans (MEPA-III) score \\\u003C13, indicating that they do not follow a Mediterranean diet.\n\nExclusion Criteria:\n\n* Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks)\n* History of colon cancer or inflammatory bowel disease (given potential untoward effects on the gut microbiome)\n* History of Clostridium difficile infection in the preceding 12 weeks; (4) unable to agree to maintain physical activity at the current level for the duration of the study\n* Currently following a Mediterranean diet, vegan diet, or dietary restrictions (e.g., religious, food intolerance\u002Fallergy) that preclude adoption of a Mediterranean diet\n* Lack of access to a space to safely store and reheat food items\n* Living in a facility that provides meals.\n* Pregnancy or breastfeeding\n* More than 7 in-patient hospital stays in the last year\n* Currently receiving dialysis treatment","ALL","18 Years",{"count":63,"type":64},30,"ESTIMATED","INTERVENTIONAL",[67],"NA","The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.",[70,71,72,9],"Sickle Cell","Sickle Cell Disease","Sickle Cell Disease Without Crisis",[74,75,76,77,78],"sickle cell","sickle cell disease","sickle cell pain","diet","Mediterranean diet","2026-04-01",{"date":81,"type":82},"2026-04-02","ACTUAL",{"date":84,"type":82},"2025-05-01",{"date":86,"type":64},"2026-12-31",{"name":5,"class":6},1]