[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631915":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":26,"locations":34,"responsibleParty":102,"collaborators":104,"id":117,"slug":10,"hasResults":118,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":118,"sex":124,"minAge":125,"maxAge":10,"enrollmentInfo":126,"targetDuration":129,"studyType":130,"phases":10,"briefSummary":131,"conditions":132,"keywords":10,"overallStatus":139,"whyStopped":10,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":149},{"fullName":5,"class":6},"Linkoeping University","OTHER_GOV",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Primary objective cohort - Lung cancer lobectomy",null,"For primary objective, patients undergoing lobectomy for lung cancer will be studied.",{"label":13,"type":10,"description":14,"interventionNames":10},"Neoadjuvant treatment cohort","As one secondary objective, patients with lung cancer undergoing neoadjuvant treatment before surgery or other non-surgical treatment will be studied separately",{"label":16,"type":10,"description":17,"interventionNames":10},"Sub-lobular resection cohort","As one secondary objective, patients undergoing sublobular resection for lung cancer will be studied separately.",{"label":19,"type":10,"description":20,"interventionNames":10},"Non-surgical treatment cohort","As one secondary objective, patients undergoing other treatment than surgery for lung cancer will be studied.",[22],{"name":23,"affiliation":24,"role":25},"Kristofer Hedman, MD, PhD","Department of Medical, Health and Caring Sciences, Linkoping University, Linkoping, Sweden","PRINCIPAL_INVESTIGATOR",[27,31],{"name":23,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+46 10 1033356","kristofer.hedman@liu.se",{"name":32,"role":28,"phone":10,"phoneExt":10,"email":33},"Karolina Kristenson","karolina.kristenson@regionostergotland.se",[35,50,63,76,89],{"facility":36,"status":10,"city":37,"state":10,"zip":10,"country":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Department of Pulmonology, Ryhov","Jönköping","Sweden",{"type":40,"coordinates":41},"Point",[42,43],14.15618,57.78145,{"lat":43,"lon":42},[46],{"name":47,"role":28,"phone":48,"phoneExt":10,"email":49},"Magnus Kentson, MD, PhD","+ 46 10-241 00 00.","magnus.kentson@rjl.se",{"facility":51,"status":10,"city":52,"state":10,"zip":10,"country":38,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Department of Pulmonology, Kalmar County Hospital","Kalmar",{"type":40,"coordinates":54},[55,56],16.36163,56.66157,{"lat":56,"lon":55},[59],{"name":60,"role":28,"phone":61,"phoneExt":10,"email":62},"Niels Hornstra, MD","+46 10-358 00 00","Niels.Hornstra@regionkalmar.se",{"facility":64,"status":10,"city":65,"state":10,"zip":10,"country":38,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Department of Pulmonology, Blekinge Hospital","Karlskrona",{"type":40,"coordinates":67},[68,69],15.58661,56.16156,{"lat":69,"lon":68},[72],{"name":73,"role":28,"phone":74,"phoneExt":10,"email":75},"Magnus Ekström, MD, PhD","+46 455-73 10 00","pmekstrom@gmail.com",{"facility":77,"status":10,"city":78,"state":10,"zip":10,"country":38,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Department of Pulmonology, University Hospital","Linköping",{"type":40,"coordinates":80},[81,82],15.62157,58.41086,{"lat":82,"lon":81},[85],{"name":86,"role":28,"phone":87,"phoneExt":10,"email":88},"Gabriel Högström, MD, PhD","+46 10 103 00 00","gabriel.hogstrom@regionostergotland.se",{"facility":90,"status":10,"city":91,"state":10,"zip":10,"country":38,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"Department of Clinical Physiology","Lund",{"type":40,"coordinates":93},[94,95],13.19321,55.70584,{"lat":95,"lon":94},[98],{"name":99,"role":28,"phone":100,"phoneExt":10,"email":101},"Henrik Mosén, MD, PhD","+46 40-33 10 00","henrik.mosen@med.lu.se",{"type":25,"investigatorFullName":23,"investigatorTitle":103,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Senior Associate Professor",[105,108,110,113,115],{"name":106,"class":107},"Region Östergötland","OTHER",{"name":109,"class":107},"Region Skane",{"name":111,"class":112},"Region Kalmar län","UNKNOWN",{"name":114,"class":112},"Region Blekinge",{"name":116,"class":6},"Region Jönköping County","100631915",false,"NCT07506889","Simplified Exercise-based Risk Assessment in Lung Cancer","EXercise-based Evaluation of Ventilatory Efficiency for enHanced Risk Assessment in Lungcancer trEatment Using End-tidal CO2: a Multicenter, Prospective Study","EXHALE-CO2","Inclusion Criteria:\n\n* Lung Cancer Diagnosis\n* Age of at least 18 years\n\nExclusion Criteria:\n\n* Not able to perform cycle ergometer exercise\n* Not able to understand spoken or written Swedish","ALL","18 Years",{"count":127,"type":128},500,"ESTIMATED","1 Year","OBSERVATIONAL","Physiological evaluation is part of the preoperative risk estimation in patients with lung cancer, and it aids in the choice of treatment. Ventilatory efficiency during exercise has emerged as a strong predictor of major postoperative complications, so far determined during a maximal cardiopulmonary exercise test. However, this test is limited by its availability and high cost, due to the requirement of high-technological equipment and advanced expertise. The current project aims to evaluate a simplified and accessible method for risk evaluation before decision on treatment in lung cancer. It builds on recent advances in technology and knowledge and combines a simple, low-intensity cycling test with measurement of ventilatory efficiency (end-tidal carbon dioxide pressure) with a handheld monitor. In a prospective, multi-center design the investigators will include patients evaluated for suspected lung cancer. The main objective is to establish threshold values for end-tidal carbon dioxide associated with low respectively high risk of major complications in patients undergoing surgery. In addition, the study aims to determine if end-tidal carbon dioxide can predict severe side-effects during neoadjuvant or curatively aiming systemic therapy. The project is closely linked to clinical practice, and the results can be easily implemented due to the simple and cost-efficient methodology. the suggested simplified approach would also allow access to physiological evaluation where more advanced methods are unavailable.",[133,134,135,136,137,138],"Lung Cancer (Diagnosis)","Lobectomy","Surgery Complications","Neoadjuvant Chemoimmunotherapy","End-Tidal Carbon Dioxide","Exercise","NOT_YET_RECRUITING","2026-04-02",{"date":142,"type":143},"2026-04-08","ACTUAL",{"date":145,"type":128},"2026-04-01",{"date":147,"type":128},"2029-12",{"name":5,"class":6},5]