[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100373409":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":29,"responsibleParty":46,"collaborators":48,"id":52,"slug":10,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Johns Hopkins University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"HIV",null,"Participants (ages 60 and above) with HIV",{"label":13,"type":10,"description":14,"interventionNames":10},"Control","Participants (ages 60 and above) without HIV",[16],{"name":17,"affiliation":5,"role":18},"Robert G Weiss, MD","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Maria Esteban, RN, BSN","CONTACT","410-955-1160","mesteba1@jh.edu",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Tricia Steinberg, RN, MSN","443-287-3469","asteinb3@jhmi.edu",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Johns Hopkins Hospital","RECRUITING","Baltimore","Maryland","21287","United States",{"type":38,"coordinates":39},"Point",[40,41],-76.61219,39.29038,{"lat":41,"lon":40},[44],{"name":45,"role":22,"phone":27,"phoneExt":10,"email":28},"Tricia Steinberg, MSN",{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[49],{"name":50,"class":51},"National Institute on Aging (NIA)","NIH","100373409",false,"NCT04142047","Skeletal Muscle Energetics and Fatiguability in Older Individuals","Inclusion Criteria:\n\n* Participants who are \\>= 60 years of age\n* HIV serostatus positive participants on stable antiretroviral therapy (ART) (no regimen change in last month) with undetectable HIV viral load (\\\u003C100 copies).\n* HIV serostatus negative participants\n\nExclusion Criteria:\n\n* Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent\n* Contraindications to MRI\n* Significant cardiovascular, pulmonary or musculoskeletal or orthopedic disease that significantly limits exercise capacity\n* Significant lower extremity peripheral vascular disease.\n* Weight greater than 350 lbs\n* Cognitive or speech impairments that would limit completion of questionnaires or fatigue reporting.",true,"ALL","60 Years","90 Years",{"count":62,"type":63},200,"ESTIMATED","OBSERVATIONAL","The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.",[9,67],"HIV Infections","2026-06-04",{"date":70,"type":71},"2026-06-08","ACTUAL",{"date":73,"type":71},"2019-09-05",{"date":75,"type":63},"2027-07-01",{"name":5,"class":6},1]