Sleep and Circadian Mechanisms in Hypertension
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-64
SponsorOregon Health and Science University
About this trial
This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).
Eligibility criteria
Qualifiers
Ages 25-64
BMI 18.5-42kg/m2
Hypertension (average resting blood pressure between 130/80 mmHg and 160/100 mmHg)
Disqualifiers
Over 5 pack-years of smoking;
Prior shift work within 12 months prior to the study;
Travel greater than three time zones for at least 3 months;
History of heart failure, cardiomyopathy, or history of bypass surgery, angioplasty, or previous myocardial infarction;
Trial design
Treatments tested in this trial
- At-home Polysomnography
- Circadian Protocol
- Rested Wakefulness Trial
- Overnight Sleep Trial
- Regularized Sleep Schedule
Treatment groups
32 Participants
are divided into 1 treatment groupLocations
1Oregon Health and Science University97239, PortlandOregon, United States
Sponsors and collaborators
Oregon Health and Science University
Lead sponsor
Source ClinicalTrials.gov