[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592160":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":24,"centralContacts":28,"locations":35,"responsibleParty":78,"collaborators":81,"id":85,"slug":33,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":86,"sex":92,"minAge":93,"maxAge":33,"enrollmentInfo":94,"targetDuration":33,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":106,"overallStatus":60,"whyStopped":33,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Erasmus Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Lynch-carriers with a (colorectal) tumor","EXPERIMENTAL","People with a newly diagnosed Lynch-associated tumor will be asked to undergo an extra blood test.",[13],"Diagnostic Test: Blood Product",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Blood Product","An (extra) blood test will be done on participants. This will be analyzed for circulating tumor DNA (ctDNA) via a multi-omics approach.",[9],[21,22,23],"Blood test","Blood draw","Liquid biopsy",[25],{"name":26,"affiliation":5,"role":27},"Anja Wagner, Dr.","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Lotte van Leeuwen, BSc","CONTACT","+31646245198",null,"l.vanleeuwen@erasmusmc.nl",[36,58],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Leiden University Medical Center","NOT_YET_RECRUITING","Leiden","South Holland","2333ZG","Netherlands",{"type":44,"coordinates":45},"Point",[46,47],4.49306,52.15833,{"lat":47,"lon":46},[50,54,56],{"name":51,"role":31,"phone":52,"phoneExt":33,"email":53},"Maartje Nielsen, Dr.","+31624240843","m.nielsen@lumc.nl",{"name":55,"role":27,"phone":33,"phoneExt":33,"email":33},"Monique van Leerdam, Prof.dr.",{"name":51,"role":57,"phone":33,"phoneExt":33,"email":33},"SUB_INVESTIGATOR",{"facility":59,"status":60,"city":61,"state":40,"zip":62,"country":42,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Erasmus MC","RECRUITING","Rotterdam","3015GD",{"type":44,"coordinates":64},[65,66],4.47917,51.9225,{"lat":66,"lon":65},[69,71,72,74,76],{"name":30,"role":31,"phone":70,"phoneExt":33,"email":34},"0646245198",{"name":26,"role":27,"phone":33,"phoneExt":33,"email":33},{"name":73,"role":57,"phone":33,"phoneExt":33,"email":33},"Saskia Wilting, Dr.",{"name":75,"role":57,"phone":33,"phoneExt":33,"email":33},"Lotte van Leeuwen, BSc.",{"name":77,"role":57,"phone":33,"phoneExt":33,"email":33},"Manon Spaander, Dr.",{"type":27,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"Lotte van Leeuwen","PhD Candidate",[82,84],{"name":83,"class":6},"Dutch Cancer Society",{"name":37,"class":6},"100592160",false,"NCT06989814","Smart Measurement of Circulating Tumor DNA","Smart Measurement of Circulating Tumor DNA: a Tumor-agnostic Computational Tool to Improve Colorectal Cancer Care","SMART","Inclusion Criteria:\n\n(suspect) Lynch Syndrome carriers who:\n\n* Have proven Lynch Syndrome (MMR-gene or EPCAM mutation), or have a proven microsatellite instability high (MSI-H)tumor;\n* Are at least 18 years old; Have been diagnosed with any form of cancer at the time of inclusion, but have had no treatment yet;\n* Have granted informed consent to participate in this study.\n\nExclusion Criteria:\n\n(suspect) Lynch Syndrome carriers who:\n\n* Are unwilling to undergo extra blood sampling;\n* Are under the age of 18;\n* Have no newly diagnosed tumors at time of inclusion;\n* Have been treated for their tumor at time of inclusion;\n* Are not able to read or understand Dutch language or are mentally not capable.","ALL","18 Years",{"count":95,"type":96},50,"ESTIMATED","INTERVENTIONAL",[99],"NA","The goal of this study is to develop a blood-test which can detect colorectal cancer in early stages.\n\nParticipants will be asked to take an extra blood test, which will be analyzed further in the lab.",[102,103,104,105],"Colorectal Neoplasms","Colorectal Neoplasms Malignant","Colorectal Neoplasms, Hereditary Nonpolyposis","Hereditary Nonpolyposis Colon Cancer",[107,108,109,110,111,112],"Liquid Biopsy","Colorectal cancer","Early detection","Prevention","Surveillance","Screening","2025-08-05",{"date":115,"type":116},"2025-08-11","ACTUAL",{"date":118,"type":116},"2025-05-16",{"date":120,"type":96},"2027-02-01",{"name":5,"class":6},2]