Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Colorado, Denver
About this trial
The purpose of this study is to evaluate the ability of a wearable Smart Underwear prototype device to quantify diet-induced changes in gut microbial hydrogen sulfide (H₂S) production. The core design is a single-site, 2-period, crossover feeding study with 6-day diet periods and an approximately 11-day washout period. Participants are fed each of two isocaloric diets designed to contrast gut microbial H₂S production (i.e., a high cysteine vs. low cysteine diet), in a random order.
Eligibility criteria
Qualifiers
None
Disqualifiers
Generally healthy volunteers defined as having no major known health conditions (e.g., diabetes, cancer, hypertension, etc.).
Normal bowel movements, with approximately 1 bowel movement reported per day
Willing to discuss flatus
Ages >18yrs
Trial design
Treatments tested in this trial
- High Cysteine Diet
- Low Cysteine Diet
Treatment groups
25 Participants
are divided into 2 treatment groupsLocations
1University of Colorado Anschutz Medical Campus80045, AuroraColorado, United States
Sponsors and collaborators
University of Colorado, Denver
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
University of Maryland, College Park
Collaborator
Source ClinicalTrials.gov