[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100057410":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":40,"centralContacts":45,"locations":55,"responsibleParty":74,"collaborators":78,"id":82,"slug":10,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":10,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":10,"studyType":95,"phases":10,"briefSummary":96,"conditions":97,"keywords":107,"overallStatus":58,"whyStopped":10,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,16,19],{"label":9,"type":10,"description":11,"interventionNames":12},"High Risk for Ovarian Cancer",null,"Women who are at increased risk of ovarian cancer based on family or personal medical history who are participating in the Northwestern Ovarian Cancer Early Detection and Prevention Program clinic.",[13,14,15],"Other: Ca-125","Other: screening questionnaire administration","Procedure: Surgery",{"label":17,"type":10,"description":18,"interventionNames":10},"Suspected or diagnosed gynecological condition","Women who are planning to undergo surgery for their gynecological condition",{"label":20,"type":10,"description":21,"interventionNames":10},"Control Group","Healthy subjects with no history of cancer and at general risk.",[23,27,33],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Ca-125","Subject's blood collected at their follow-up blood draw will be assessed for biomarkers that could lead to a panel for detecting early stage ovarian cancer.",[9],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"screening questionnaire administration","Questionnaires designed to assess quality of life for women at increased risk of ovarian cancer will be administered to the subjects. Clinical data will also be collected.",[9],[32],"Questionnaire",{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"PROCEDURE","Surgery","Subjects will be assessed for high risk factors.",[9],[39],"BSO, fallopian tubes, TAH, hysterectomy, bilateral salpingectomy, STIC",[41],{"name":42,"affiliation":43,"role":44},"Lee P. Shulman, MD","Robert H. Lurie Cancer Center","STUDY_CHAIR",[46,51],{"name":47,"role":48,"phone":49,"phoneExt":10,"email":50},"Takelia Walker","CONTACT","3125034802","takelia-watson@northwestern.edu",{"name":52,"role":48,"phone":53,"phoneExt":10,"email":54},"Anne Grace","312-503-4165","anne@northwestern.edu",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Robert H. Lurie Comprehensive Cancer Center at Northwestern University","RECRUITING","Chicago","Illinois","60611-3013","United States",{"type":64,"coordinates":65},"Point",[66,67],-87.65005,41.85003,{"lat":67,"lon":66},[70],{"name":71,"role":48,"phone":72,"phoneExt":10,"email":73},"Clinical Trials Office - Robert H. Lurie Comprehensive Cancer","312-695-1301","cancer@northwestern.edu",{"type":75,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Lee Shulman","Professor",[79],{"name":80,"class":81},"National Cancer Institute (NCI)","NIH","100057410",false,"NCT00005095","Specimen and Data Study for Ovarian Cancer Early Detection and Prevention","Northwestern Ovarian Cancer Early Detection & Prevention Program: A Specimen and Data Study","DISEASE CHARACTERISTICS:\n\n* Meets one of the following criteria:\n\n  * Considered to be at increased risk for developing ovarian cancer, as defined by one of the following:\n\n    * Has at least one first-degree relative (mother, sister, or daughter) with ovarian, primary peritoneal, or fallopian tube cancer\n    * Has at least two first or second degree relatives diagnosed before age 50 with either ovarian, primary peritoneal, fallopian tube, and\u002For pancreatic cancer who have tested positive for hereditary cancer syndrome that includes an increased risk of gynecologic cancer (e.g., BRCA1\u002F2 or Lynch Syndrome)or have increased risk as deemed by a certified genetic counselor\n    * A personal or family history of a hereditary cancer syndrome that includes an increased risk of gynecologic cancer\n    * Increased risk as deemed by a certified genetic counselor\n  * Undergoing surgery for a gynecologic condition, including any of the following:\n\n    * Diagnosis of a reproductive cancer\n    * Benign gynecological condition (e.g., uterine leiomyomata, endometriosis, pelvic inflammatory disease, or follicular or corpus luteum ovarian cysts)\n    * Highly suspicious adnexal mass\n    * Risk-reducing prophylactic oophorectomy\n\nPATIENT CHARACTERISTICS:\n\nAge\n\n* Between the ages of 18 and 80",true,"FEMALE","18 Years","80 Years",{"count":93,"type":94},6000,"ESTIMATED","OBSERVATIONAL","RATIONALE: To improve strategies for detection and prevention of early-stage disease.\n\nPURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer among the high risk population and those who have the disease.",[98,99,100,101,102,103,104,105,106],"Cervical Cancer","Endometrial Cancer","Fallopian Tube Cancer","Hereditary Breast\u002FOvarian Cancer (brca1, brca2)","Ovarian Cancer","Sarcoma","Uterine Leiomyomata","Vaginal Cancer","Vulvar Cancer",[108,109,110,111,112,113,114,115,116,117,118,119],"ovarian epithelial cancer","hereditary breast\u002Fovarian cancer (BRCA1, BRCA2)","fallopian tube cancer","ovarian germ cell tumor","ovarian sarcoma","ovarian stromal cancer","endometrial cancer","uterine sarcoma","vaginal cancer","cervical cancer","vulvar cancer","uterine leiomyomata","2025-02-26",{"date":122,"type":123},"2025-02-28","ACTUAL",{"date":125,"type":123},"2000-03",{"date":127,"type":94},"2040-12",{"name":5,"class":6},1]