[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628626":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":58,"collaborators":61,"id":68,"slug":25,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":25,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Brigham and Women's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pilates","EXPERIMENTAL","6 weeks of once weekly in-person Pilates-based exercise classes",[13],"Behavioral: Pilates",{"label":15,"type":16,"description":17,"interventionNames":18},"Enhanced Usual Care","ACTIVE_COMPARATOR","6 weeks of once weekly educational seminars pertaining to hypermobility symptom management",[19],"Behavioral: Education",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Education","Educational seminars pertaining to hypermobility symptom management",[15],[31],{"name":32,"affiliation":5,"role":33},"Samantha Meints, PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Stephanie Voss, PhD","CONTACT","6177329181","svoss2@bwh.harvard.edu",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Chestnut Hill","Massachusetts","01467","United States",{"type":48,"coordinates":49},"Point",[50,51],-71.16616,42.33065,{"lat":51,"lon":50},[54],{"name":55,"role":37,"phone":56,"phoneExt":25,"email":57},"Samantha M Meints","6177329014","smeints@bwh.harvard.edu",{"type":33,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Samantha Meints","Assistant Professor",[62,65],{"name":63,"class":64},"Bernard Osher Foundation","UNKNOWN",{"name":66,"class":67},"National Institutes of Health (NIH)","NIH","100628626",false,"NCT07464093","STABLE Pilates for Hypermobility","Pilates for Hypermobility: A Pilot Feasibility Study","STABLE","Inclusion Criteria:\n\n* ≥ 18 years old;\n* Self-reported hypermobility with confirmed or suspected diagnosis of hEDS\u002FHSD;\n* Self-reported persistent pain ≥ 3 months;\n* A minimum of 3\u002F10 self-reported pain intensity in the past week\n* Able to get on and off the floor without assistance;\n* Able to communicate fluently in English; and\n* Able to provide written, informed consent\n\nExclusion Criteria:\n\n* Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min\u002Fweek over the past 6 months;\n* Recent surgery or acute bone, joint or nerve injury (\\\u003C6 months);\n* Have a history of a severe or progressive neurological or movement disorder;\n* Pregnant, planning to become pregnant during the study, or currently breast feeding;\n* Unable to get on and off the floor without assistance;\n* Unable to complete study procedures due to cognitive impairment;\n* Unable to provide written, informed consent; or\n* Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.","ALL","18 Years",{"count":78,"type":79},100,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.",[85,86,87],"Ehlers-Danlos Syndrome (EDS)","Hypermobile EDS (hEDS)","Hypermobile Spectrum Disorder",[89,90,91],"hypermobility","pilates","pain","2026-06-09",{"date":94,"type":95},"2026-06-11","ACTUAL",{"date":97,"type":79},"2026-07",{"date":99,"type":79},"2027-12",{"name":5,"class":6},1]