[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100460251":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":49,"collaborators":11,"id":51,"slug":11,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":11,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":34,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University of Minnesota","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Vibrotactile Stimulation","EXPERIMENTAL",null,[13],"Device: Vibrotactile Stimulation",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":11},"DEVICE","Small electric motors, similar to a vibrating cell phone or gaming joystick, deliver vibration to the throat. Participants will assess cough symptoms throughout the study period.",[9],[20],{"name":21,"affiliation":5,"role":22},"Stephanie Misono","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Clinical Research Coordinators Ashley Ramaker, MS or colleagues","CONTACT","612-625-3278","coughstudy@umn.edu",{"name":30,"role":26,"phone":11,"phoneExt":11,"email":31},"Ali Stockness","nicho656@umn.edu",[33],{"facility":5,"status":34,"city":35,"state":36,"zip":37,"country":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Minneapolis","Minnesota","55455","United States",{"type":40,"coordinates":41},"Point",[42,43],-93.26384,44.97997,{"lat":43,"lon":42},[46],{"name":21,"role":26,"phone":47,"phoneExt":11,"email":48},"612-626-5526","smisono@umn.edu",{"type":50,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100460251",false,"NCT05273190","Stimulation of the Larynx to Treat Unexplained Chronic Cough","Vibrotactile Stimulation of the Larynx to Treat Unexplained Chronic Cough","Inclusion Criteria:\n\n* Adults aged 18-88\n* \\>8 weeks of cough\n* Cough visual analogue scale (VAS): Rating of 30 or greater on a 0-100 cough severity scale\n* Ability to provide informed consent and independently complete questionnaires\n* Ability to read and speak English\n\nExclusion Criteria:\n\n* Electronic implants (e.g., pacemaker)\n* Currently doing speech therapy for cough\n* Contraindications to safe or effective VTS device use\n* No regular access to wifi internet Neuromuscular impairment that may affect cough\u002Flaryngeal sensation and\u002For function (e.g., multiple system atrophy, Parkinson, CVA, vocal fold paralysis or paresis)\n* Untreated carotid disease\n* BMI \\> 40 (for transmission of VTS through soft tissue)\n* Current or recent (quit \\\u003C 3 months ago) smoking\n* Known currently infectious cause for cough (e.g., TB, pertussis, COVID)\n* History of known or suspected aspiration pneumonia\n* Diagnosis or clinical suspicion of chronic obstructive pulmonary disease (COPD)\n* Diagnosis or clinical suspicion of interstitial lung disease (ILD)\n* Unmanaged reflux\n* Unmanaged allergies\u002Fpostnasal drip","ALL","18 Years","88 Years",{"count":61,"type":62},60,"ESTIMATED","INTERVENTIONAL",[65],"NA","Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.",[68],"Cough",[70],"Chronic cough","2026-06-12",{"date":73,"type":74},"2026-06-15","ACTUAL",{"date":76,"type":74},"2021-07-13",{"date":78,"type":62},"2027-06-30",{"name":5,"class":6},1]