[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628436":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":10,"centralContacts":34,"locations":40,"responsibleParty":59,"collaborators":10,"id":63,"slug":10,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":10,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":10,"studyType":75,"phases":10,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sleeve Gastrectomy (SG)",null,"Patients undergoing primary laparoscopic sleeve gastrectomy as treatment for morbid obesity. This group serves as the restrictive procedure comparator.",[13],"Procedure: Laparoscopic Sleeve Gastrectomy",{"label":15,"type":10,"description":16,"interventionNames":17},"Gastric Bypass (MGB\u002FRYGB)","Patients undergoing primary laparoscopic gastric bypass, including both Mini Gastric Bypass (MGB) and Roux-en-Y Gastric Bypass (RYGB), as treatment for morbid obesity. This group serves as the diversionary procedure comparator.",[18,19],"Procedure: Mini Gastric Bypass","Procedure: Roux-en-Y Gastric Bypass",[21,26,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"PROCEDURE","Laparoscopic Sleeve Gastrectomy","Laparoscopic sleeve gastrectomy performed using a standard technique with a 36-Fr bougie, transecting the stomach starting 4-6 cm from the pylorus, excising the entire greater curvature and fundus. The staple line is inspected for hemostasis and leakage.",[9],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Mini Gastric Bypass","Laparoscopic mini gastric bypass performed using a standard technique with a long gastric tube created from the angle of His to the antrum, and a loop gastrojejunostomy with a biliopancreatic limb of 200 cm.",[15],{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"Roux-en-Y Gastric Bypass","Laparoscopic Roux-en-Y gastric bypass performed using a standard antecolic, antegastric technique. A small 30-mL gastric pouch is created. The biliopancreatic limb is 70-150 cm, and the alimentary (Roux) limb is 100-150 cm. Jejunojejunostomy is performed to restore continuity.",[15],[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Ahmed Eid Aziz, Lecturer","CONTACT","+201127060844","Ahmed-eid@kasralainy.edu.eg",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Faculty of Medicine Cairo University","RECRUITING","Cairo","Al-Manial Cairo","11956","Egypt",{"type":49,"coordinates":50},"Point",[51,52],31.24967,30.06263,{"lat":52,"lon":51},[55],{"name":56,"role":37,"phone":57,"phoneExt":10,"email":58},"Mahmoud El Azhary, Lecturer","+201064110221","Mahmoud.azhary@kasralainy.edu.eg",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ahmed Eid Ali Ahmed Aziz","Lecturer","100628436",false,"NCT07461610","Stool Analysis After Sleeve Gastrectomy vs Gastric Bypass","Routine Stool Parameters Six Months After Sleeve Gastrectomy vs. Gastric Bypass: Correlation With Weight Loss and Metabolic Outcomes","Inclusion Criteria:\n\n* Male and female patients aged 18 to 60 years\n* Body Mass Index (BMI) ≥ 40 kg\u002Fm², OR BMI ≥ 35 kg\u002Fm² with at least one obesity-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, osteoarthritis, obstructive sleep apnea)\n* Patients scheduled for primary laparoscopic bariatric surgery (either SG or Gastric Bypass \\[MGB or RYGB\\]) at Kasr Al-Ainy University Hospitals\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years or \\> 60 years\n* Previous bariatric surgery or major gastrointestinal surgery (gastric, intestinal, or colorectal resection)\n* Chronic kidney disease (eGFR \\\u003C 60 mL\u002Fmin\u002F1.73m²) or previous renal transplant\n* Chronic liver disease (cirrhosis, chronic hepatitis) or liver failure\n* Chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis), celiac disease, or chronic pancreatitis\n* Active malignancy or history of chemotherapy\u002Fradiotherapy in the past 5 years\n* Pregnancy or breastfeeding\n* Chronic alcohol abuse or substance abuse\n* Use of antibiotics, probiotics, or prebiotics within 4 weeks prior to stool sample collection (to avoid confounding effects on gut flora)\n* Acute gastrointestinal infection at the time of sample collection","ALL","18 Years","60 Years",{"count":73,"type":74},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn whether routine stool tests can detect changes in gut function 6 months after two common types of weight loss surgery: sleeve gastrectomy and gastric bypass (including mini gastric bypass and Roux-en-Y gastric bypass). The main questions it aims to answer are:\n\nDo stool tests show more signs of undigested food or carbohydrate malabsorption after gastric bypass compared to sleeve gastrectomy?\n\nDo signs of gut inflammation in stool (like fecal calprotectin) decrease after surgery, and does this relate to improvements in blood sugar and weight loss?\n\nCan simple stool test results at 6 months predict how much weight a person loses or how well their diabetes improves?\n\nResearchers will compare stool test results between the two surgery groups (sleeve gastrectomy vs. gastric bypass) to see if the type of surgery leads to different changes in gut health.\n\nParticipants will:\n\nProvide a stool sample before surgery and again 6 months after surgery\n\nProvide a blood sample at the same time points to measure weight, blood sugar, and cholesterol\n\nUndergo their planned weight loss surgery as part of their regular medical care",[78],"Morbid Obesity",[80,81,82,83,84,85],"Bariatric Surgery","Stool Analysis","Fecal Calprotectin","Reducing Substances","Maldigestion","Gut Microbiota","2026-05-14",{"date":88,"type":89},"2026-05-18","ACTUAL",{"date":91,"type":89},"2026-04-05",{"date":93,"type":74},"2026-12",{"name":5,"class":6},1]