[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100404837":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":17,"centralContacts":21,"locations":31,"responsibleParty":68,"collaborators":70,"id":74,"slug":16,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":16,"eligibilityCriteria":78,"healthyVolunteers":75,"sex":79,"minAge":80,"maxAge":16,"enrollmentInfo":81,"targetDuration":16,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":16,"overallStatus":34,"whyStopped":16,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Yale University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Mental Stress","Patients will undergo a lab mental stress protocol, and a field protocol using ecological momentary assessment (EMA) to test the effects of psychological stress and negative emotion on PAP in HF patients.",[12],"Other: Mental Stress",[14],{"type":6,"name":9,"description":10,"armGroupLabels":15,"otherNames":16},[9],null,[18],{"name":19,"affiliation":5,"role":20},"Rachel Lampert, MD","PRINCIPAL_INVESTIGATOR",[22,26],{"name":19,"role":23,"phone":24,"phoneExt":16,"email":25},"CONTACT","(203) 737-4068","rachel.lampert@yale.edu",{"name":27,"role":23,"phone":28,"phoneExt":29,"email":30},"Matthew Burg","203-932-5711","3268","matthew.burg@yale.edu",[32,56],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"St. Francis Hospital","RECRUITING","Hartford","Connecticut","06105","United States",{"type":40,"coordinates":41},"Point",[42,43],-72.68509,41.76371,{"lat":43,"lon":42},[46,50,54],{"name":47,"role":23,"phone":48,"phoneExt":16,"email":49},"Colleen Watters, APRN","860-714-6178","colleen.watters@trinityhealthofne.org",{"name":51,"role":23,"phone":52,"phoneExt":16,"email":53},"Megan Evjen, RN","860-714-4860","MEvjen@TrinityHealthOfNE.org",{"name":55,"role":20,"phone":16,"phoneExt":16,"email":16},"Saima Husain, MD",{"facility":5,"status":34,"city":57,"state":36,"zip":58,"country":38,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"New Haven","06511",{"type":40,"coordinates":60},[61,62],-72.92816,41.30815,{"lat":62,"lon":61},[65],{"name":66,"role":23,"phone":67,"phoneExt":16,"email":25},"Rachel Lampert","203-737-4068",{"type":69,"investigatorFullName":16,"investigatorTitle":16,"investigatorAffiliation":16,"oldNameTitle":16,"oldOrganization":16},"SPONSOR",[71],{"name":72,"class":73},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100404837",false,"NCT04551560","Stress and Congestive Heart Failure","Inclusion Criteria:\n\n-Heart failure patients over 18 who have or will be receiving a Cardiomems implanted PAP monitor.\n\nExclusion Criteria:\n\n* Patients who are unable to perform EMA or laboratory assessments due to cognitive, visual, language, or other disabilities will be excluded.\n* Patients with Class IV heart failure will also be excluded, as they are already maximally decompensated, and a ceiling\u002Ffloor effect would preclude effects of stress.\n* Patients with conditions other than heart failure that affect PA pressures (e.g. dialysis).\n* Patients with physical conditions that interfere with study participation.\n* Patients non-compliant with their PAP monitoring.\n* Patients with chronic opioid use will be excluded.","ALL","18 Years",{"count":82,"type":83},112,"ESTIMATED","INTERVENTIONAL",[86],"NA","The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF.",[89],"Congestive Heart Failure","2026-01-26",{"date":92,"type":93},"2026-01-27","ACTUAL",{"date":95,"type":93},"2020-12-02",{"date":97,"type":83},"2026-04-30",{"name":5,"class":6},2]