Health Trials

About this trial

The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes. Mono-factor interventions targeting and improving these risky lifestyles have been shown to reduce the risk at surgery, but there is a lack of systematic assessment of all five lifestyles of the patient before surgery and related optimization.

This study aims to evaluate the effect of intensive combined lifestyle interventions (the STRONG programme) compared with treatment as usual in patients undergoing ventral hernia repair on postoperative complications, health, and costs on short and longer term.

The hypothesis is that the STRONG programme will halve the complication rates within 30 days.

Eligibility criteria

Qualifiers

Participants ≥18 years scheduled for ventral hernia repair (defect smaller than 8cm)

Enough time for at least 4 weeks of prehabilitation

Screened positive for at least 1 risky SNAP factor

Signed informed consent

Disqualifiers

Ventral hernia repairs with defect larger than 8 cm

Pregnancy/breastfeeding

Allergy/other contradiction to pharmaceutical and/or nutritional support

Contradiction to exercise

Trial design

Treatments tested in this trial

  • Prehabilitation (the STRONG programme)

Treatment groups

400 Participants
are divided into 2 treatment groups

Locations

3
Copenhagen University Hospital at Herlev2730, Herlev Denmark
Holbaek Sygehus4300, Holbæk Denmark
Zealand University Hospital4600, Køge Denmark

Sponsors and collaborators

Bispebjerg Hospital

Lead sponsor

Copenhagen University Hospital at Herlev

Collaborator

Zealand University Hospital

Collaborator

Holbaek Sygehus

Collaborator

Source ClinicalTrials.gov