Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
ConditionLymphedema
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorUniversity Hospital, Toulouse
About this trial
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose tissue deposition in the affected area. It can be an inherited condition (primary lymphedema) or occurs after cancer surgery and lymph node removal (secondary lymphedema). It causes a significant morbidity and is a common disabling disease affecting more than 200 million people worldwide, however there is no curative treatment for primary or secondary lymphedema.
Eligibility criteria
Qualifiers
Patients in who developed primary lymphedema or secondary lymphedema after breast cancer treatment.
Male and female over the age of 18 and under 75.
Patient affiliated to a social security scheme in France.
Patient having signed informed consent prior to inclusion in the study and prior to any specific procedure for the study.
Disqualifiers
Patients with strong suspicion or with active bacterial or fungal infection.
Patient with venous insufficiency associated with lymphedema.
Patient with a history of deep venous thrombosis on the limb with lymphedema.
History of chronic inflammatory disease.
Trial design
Treatments tested in this trial
- Micro-biopsies
Treatment groups
60 Participants
are divided into 2 treatment groupsLocations
1Toulouse Hospital Toulouse France
Sponsors and collaborators
University Hospital, Toulouse
Lead sponsor
Source ClinicalTrials.gov