Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma

ConditionGlaucoma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNantes University Hospital

About this trial

Glaucoma is a chronic disease of the optic nerve, characterized by progressive loss of nerve cells in the retina, leading to progressive loss of peripheral and central vision. There are in fact several types of glaucoma, which is the world's second leading cause of blindness after cataracts, and the leading cause of irreversible blindness.

To date, to our knowledge, there is no work analyzing the progression of angiographic OCT in patients with glaucoma.

The main aim of this study is to compare the 3-year progression rate of 3 examinations in advanced glaucoma patients: one functional (visual field) and two anatomical (OCTa and OCTrnfl).

Eligibility criteria

Qualifiers

Men and women aged 18 and over

Patient with glaucoma followed in the ophthalmology department of Nantes University Hospital

mean visual field deficit (MD) >10dB

Disqualifiers

Retinal vascular pathology (moderate to severe non-proliferative diabetic retinopathy, complicated diabetic retinopathy, OVCR/OBVR, OACR/OBAR, NOIAA...) Non-glaucomatous optic neuropathy, neurological pathology leading to visual field deficit (stroke with HLH, quadranopsia, chiasmatic Sd...)

PPR (retinal PanPhotocoagulation), retinal cerclage

Retinal pathology leading to visual field impairment (e.g. retinitis pigmentosa)

AMD and other macular pathologies that can lead to central visual field deficits

Trial design

Treatments tested in this trial

  • OCT

Treatment groups

No treatment groups listed

Locations

2
CHU Nantes44000, NantesNantes, France
Jean-Baptiste Ducloyer44093, NantesNantes, France

Sponsors and collaborators

Nantes University Hospital

Lead sponsor