[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525186":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":19,"interventions":29,"overallOfficials":35,"centralContacts":39,"locations":13,"responsibleParty":44,"collaborators":13,"id":48,"slug":13,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":13,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":13,"studyType":60,"phases":13,"briefSummary":61,"conditions":62,"keywords":13,"overallStatus":64,"whyStopped":13,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":13},{"fullName":5,"class":6},"Qianfoshan Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"AUNIP expression in serum","Serum AUNIP expression is detected by ELISA kit. The results will be recorded seperately.","through study completion, an average of 3 year",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","PROSPECTIVE","Blood of all study participants of cervical cancer patients are collected to detect the expression of AUNIP, analyze the statistical correlation between the expression of cervical cancer AUNIP and clinicopathological parameters of patients, and preliminarily understand the expression of AUNIP in cervical cancer tumor tissues and its clinical diagnostic and progniostic value.","In this study, 150 patients with cervical cancer in the First Affiliated Hospital of Shandong First Medical University (Shandong Qianfoshan Hospital) are selected as the study group. 150 healthy women are taken as control group during the same period.",[20,25],{"label":21,"type":13,"description":22,"interventionNames":23},"study group","Women aged 20-60; There is a definite pathological diagnosis of cervical cancer",[24],"Diagnostic Test: Detection of serum AUNIP expression",{"label":26,"type":13,"description":27,"interventionNames":28},"Healthy control group","Women aged 20-60; No tumors in the uterus or other parts of the body; No inflammatory disease; Blood routine and blood biochemical tests are normal.",[24],[30],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":13},"DIAGNOSTIC_TEST","Detection of serum AUNIP expression","The experiment is carried out according to the ELISA kit instructions, and the absorbance optic density (OD) value of the enzyme labeler at 450 nm is read. The protein concentration of AUNIP in the serum sample is calculated according to the standard curve.",[26,21],[36],{"name":37,"affiliation":5,"role":38},"Lin Yuan, Ph.D.","PRINCIPAL_INVESTIGATOR",[40],{"name":37,"role":41,"phone":42,"phoneExt":13,"email":43},"CONTACT","0531-89269678","yuanl@sdfmu.edu.cn",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"SPONSOR_INVESTIGATOR","Lin Yuan","Principal Investigator","100525186",false,"NCT06118463","Study on AUNIP as a Novel Tumor Marker for Cervical Cancer","Inclusion Criteria:\n\nStudy group inclusion criteria:\n\n* Women aged 20-60\n* There is a definite pathological diagnosis of cervical cancer\n\nHealthy control group:\n\n* Women aged 20-60\n* No tumors in the uterus or other parts of the body\n* No inflammatory disease\n* Blood routine and blood biochemical tests are normal\n\nExclusion Criteria:\n\nExclusion criteria of the study group:\n\n* There are other lesions in the uterus and uterine adnexa\n\nExclusion criteria of healthy control group:\n\n* Pregnant, lactating or menarche women\n* Women who are undergoing human papillomavirus (HPV) vaccination",true,"FEMALE","20 Years","60 Years",{"count":58,"type":59},300,"ESTIMATED","OBSERVATIONAL","To detect the expression of AUNIP in cervical cancer serum, and to clarify its diagnostic and prognostic value.",[63],"Cervical Cancer","NOT_YET_RECRUITING","2023-11-06",{"date":67,"type":68},"2023-11-09","ACTUAL",{"date":70,"type":59},"2024-01-01",{"date":72,"type":59},"2029-01-01",{"name":46,"class":6}]