[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572683":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":29,"locations":35,"responsibleParty":109,"collaborators":111,"id":115,"slug":28,"hasResults":116,"nctId":117,"briefTitle":118,"officialTitle":118,"acronym":28,"eligibilityCriteria":119,"healthyVolunteers":116,"sex":120,"minAge":121,"maxAge":28,"enrollmentInfo":122,"targetDuration":28,"studyType":125,"phases":126,"briefSummary":128,"conditions":129,"keywords":134,"overallStatus":38,"whyStopped":28,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":150},{"fullName":5,"class":6},"Artur Salgado SA","INDUSTRY",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Long-bone injuries","EXPERIMENTAL","Group formed by subjects with long-bone injuries treated using AdvanCore blocks, wedges, or granules.",[13],"Procedure: AdvanCore bone grafting",{"label":15,"type":10,"description":16,"interventionNames":17},"Spine injuries","Group formed by subjects with spine injuries treated using AdvanCore granules.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Maxillofacial injuries","Group formed by subjects with maxillofacial injuries treated using AdvanCore granules.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","AdvanCore bone grafting","AdvanCore medical device is implanted making sure that is in direct contact with all surfaces of the defect area.",[9,19,15],null,[30],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},"Francisca C Costa","CONTACT","+351253794649","f.costa@artursalgado.pt",[36,57,75,92],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Unidade Local de Saúde do Alto Ave","RECRUITING","Guimarães","Braga District","4835-044","Portugal",{"type":44,"coordinates":45},"Point",[46,47],-8.29619,41.44443,{"lat":47,"lon":46},[50,54],{"name":51,"role":32,"phone":52,"phoneExt":28,"email":53},"Ana Sofia F Costa","+351253540330","sofiafreitascosta@hospitaldeguimaraes.min-saude.pt",{"name":55,"role":56,"phone":28,"phoneExt":28,"email":28},"Carlos A Vilela Gomes, Orthopaedic surgeon","PRINCIPAL_INVESTIGATOR",{"facility":58,"status":59,"city":60,"state":61,"zip":62,"country":42,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Unidade Local de Saúde de São João","NOT_YET_RECRUITING","Porto","Porto District","4200-319",{"type":44,"coordinates":64},[65,66],-8.61097,41.1485,{"lat":66,"lon":65},[69,73],{"name":70,"role":32,"phone":71,"phoneExt":28,"email":72},"Teresa Burnay","+351225512100","ca@chsj.min-saude.pt",{"name":74,"role":56,"phone":28,"phoneExt":28,"email":28},"Teresa Burnay, Maxillofacial surgeon",{"facility":76,"status":59,"city":77,"state":78,"zip":79,"country":42,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Unidade Local de Saúde do Médio Tejo","Tomar","Santarém District","2304-909",{"type":44,"coordinates":81},[82,83],-8.40924,39.60199,{"lat":83,"lon":82},[86,90],{"name":87,"role":32,"phone":88,"phoneExt":28,"email":89},"Ana Rita B Reis","+351249320100","rita.reis@ulsmt.min-saude.pt",{"name":91,"role":56,"phone":28,"phoneExt":28,"email":28},"Amílcar J Valverde, Orthopaedic surgeon",{"facility":93,"status":38,"city":94,"state":95,"zip":96,"country":42,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Unidade Local de Saúde de Trás-os-Montes e Alto Douro","Lordelo","Vila Real District","5000-508",{"type":44,"coordinates":98},[99,100],-7.76652,41.31777,{"lat":100,"lon":99},[103,107],{"name":104,"role":32,"phone":105,"phoneExt":28,"email":106},"Catarina S dos Santos","+351259300500","cslsantos@chtmad.min-saude.pt",{"name":108,"role":56,"phone":28,"phoneExt":28,"email":28},"Carlos E Pintado, Orthopeadic Surgeon",{"type":110,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[112],{"name":113,"class":114},"NAMSA","OTHER","100572683",false,"NCT06736457","Study on Safety and Performance of AdvanCore Bone Void Filler","Inclusion Criteria:\n\n* Adult subjects ≥ 18 years old, male or female.\n* Subjects who are eligible for a bone grafting\u002Fbone void filler procedure.\n* Subjects with bone lesions beyond the limits of the bone's self-healing ability.\n* Subjects, and\u002For an authorized representative, who are willing and capable of providing informed consent, participating in all testing associated with this clinical investigation at an approved clinical investigational center.\n* Subjects with only one fracture susceptible to treatment with an AdvanCore implant.\n\nExclusion Criteria:\n\n* Subjects with any AdvanCore contraindication for implantation or use.\n* Subjects with hypersensitivity to any of the AdvanCore components.\n* Subjects with infections or soft\u002Fgranulation tissue in the area to place bone graft.\n* Subjects who are currently enrolled in another investigational study or registry that would directly interfere with the current study.\n* Women who are breastfeeding or of childbearing potential who are, or plan to become, pregnant during the time of the study (method of assessment upon physician's discretion).","ALL","18 Years",{"count":123,"type":124},190,"ESTIMATED","INTERVENTIONAL",[127],"NA","The objective of this study is to evaluate the safety and performance of AdvanCore implantable bone graft through a 12-month follow-up period in a prospective, parallel-group design, non-controlled, open label, multi-center and real-world setting study. This study is intended to satisfy post-market clinical follow-up requirements of CE Mark in Europe.",[130,131,132,133],"Bone Fractures","Bone Defects","Bone Loss","Bone Graft",[135,136,137,138,139,140],"Bone graft","Bone substitute","Bone regeneration","AdvanCore","Beta-Tricalcium Phosphate","Synthetic bone graft","2025-05-30",{"date":143,"type":144},"2025-05-31","ACTUAL",{"date":146,"type":144},"2025-05-29",{"date":148,"type":124},"2026-10",{"name":5,"class":6},4]