Health Trials

Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery

ConditionCranial Defect
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorThe Affiliated Hospital Of Guizhou Medical University

About this trial

To compare the neurological recovery and complication rate of autogenous cranioplasty(CP) within 6 weeks after decompressive craniectomy (DC) with that of autogenous cranioplasty within 3\~6 months after DC.

Eligibility criteria

Qualifiers

Decompressive craniectomy due to craniocerebral trauma, cerebral ischemia and cerebral hemorrhage.

Age 18 - 80 years.

The first time for cranial repair.

unilateral skull defect.

Disqualifiers

Poor healing of skin flap (active infection, non-healing, necrosis, sinus, thin or poor blood supply, etc.).

Fracture of bone flap ≥2 pieces, partial open fracture

Intracranial infection before operation.

Severe bone metabolic diseases.

Trial design

Treatments tested in this trial

  • operation opportunity-within 6 weeks after the DC operation.
  • operation opportunity-within 90 to 180 days after the DC operation.

Treatment groups

582 Participants
are divided into 2 treatment groups

Locations

7
Anshun People's Hospital (Ward One)561000, AnshunGuizhou, China
Anshun People's Hospital (Ward Two)561000, AnshunGuizhou, China
The First People's Hospital of Bijie City BijieGuizhou, China
Guizhou Provincial Workers' Hospital GuiyangGuizhou, China

Sponsors and collaborators

The Affiliated Hospital Of Guizhou Medical University

Lead sponsor

Source ClinicalTrials.gov