[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607052":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":128,"collaborators":25,"id":131,"slug":25,"hasResults":132,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":132,"sex":138,"minAge":139,"maxAge":140,"enrollmentInfo":141,"targetDuration":25,"studyType":144,"phases":145,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":155,"whyStopped":25,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":165},{"fullName":5,"class":6},"The Affiliated Hospital Of Guizhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"experimental group","EXPERIMENTAL","The autologous skull repair surgery will be completed within 6 weeks after the DC operation.",[13],"Procedure: operation opportunity-within 6 weeks after the DC operation.",{"label":15,"type":16,"description":17,"interventionNames":18},"control group","ACTIVE_COMPARATOR","The surgery should be completed within 90 to 180 days after DC.",[19],"Procedure: operation opportunity-within 90 to 180 days after the DC operation.",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","operation opportunity-within 6 weeks after the DC operation.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"operation opportunity-within 90 to 180 days after the DC operation.","The autologous skull repair surgery should be completed within 90 to 180 days after DC.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Kaya Xu","CONTACT","13984843194","xkaya@sina.com",[37,54,64,75,88,101,114],{"facility":38,"status":25,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Anshun People's Hospital (Ward One)","Anshun","Guizhou","561000","China",{"type":44,"coordinates":45},"Point",[46,47],105.93333,26.25,{"lat":47,"lon":46},[50],{"name":51,"role":33,"phone":52,"phoneExt":25,"email":53},"Wenyuan Tang, MM","13985312332","13985312332@qq.com",{"facility":55,"status":25,"city":39,"state":40,"zip":41,"country":42,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"Anshun People's Hospital (Ward Two)",{"type":44,"coordinates":57},[46,47],{"lat":47,"lon":46},[60],{"name":61,"role":33,"phone":62,"phoneExt":25,"email":63},"Hui Shuai, BMed","13985729194","13985729194@qq.com",{"facility":65,"status":25,"city":66,"state":40,"zip":25,"country":42,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"The First People's Hospital of Bijie City","Bijie",{"type":44,"coordinates":68},[69,70],105.28627,27.30193,{"lat":70,"lon":69},[73],{"name":74,"role":33,"phone":25,"phoneExt":25,"email":25},"Bingxiang Xiao, MD",{"facility":76,"status":25,"city":77,"state":40,"zip":25,"country":42,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Guizhou Provincial Workers' Hospital","Guiyang",{"type":44,"coordinates":79},[80,81],106.71667,26.58333,{"lat":81,"lon":80},[84],{"name":85,"role":33,"phone":86,"phoneExt":25,"email":87},"Guanghui Ran, BMed","18286059351","18286059351@qq.com",{"facility":89,"status":25,"city":90,"state":40,"zip":25,"country":42,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Qianfengdong Prefecture People's Hospital","Kaili",{"type":44,"coordinates":92},[93,94],107.97972,26.58583,{"lat":94,"lon":93},[97],{"name":98,"role":33,"phone":99,"phoneExt":25,"email":100},"Jian Shen, MM","15985527337","15985527337@qq.com",{"facility":102,"status":25,"city":103,"state":40,"zip":25,"country":42,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"Zunyi Medical University Affiliated Hospital","Zunyi",{"type":44,"coordinates":105},[106,107],106.90722,27.68667,{"lat":107,"lon":106},[110],{"name":111,"role":33,"phone":112,"phoneExt":25,"email":113},"Haitao Wu","18984980327","18984980327@qq.com",{"facility":115,"status":25,"city":116,"state":117,"zip":25,"country":42,"cosmosGeoPoint":118,"geoPoint":122,"contacts":123},"Neijiang First People's Hospital","Neijiang","Sichuan",{"type":44,"coordinates":119},[120,121],105.06216,29.58354,{"lat":121,"lon":120},[124],{"name":125,"role":33,"phone":126,"phoneExt":25,"email":127},"Cong Liu","13438640683","13438640683@qq.com",{"type":129,"investigatorFullName":32,"investigatorTitle":130,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100607052",false,"NCT07183540","Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery","Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery: a Multicenter, Prospective, Open-label, Endpoint-blinded, Randomized Controlled Study","FAST-ECP","Inclusion Criteria:\n\n1. Decompressive craniectomy due to craniocerebral trauma, cerebral ischemia and cerebral hemorrhage.\n2. Age 18 - 80 years.\n3. The first time for cranial repair.\n4. unilateral skull defect.\n5. Compliant with recommended decompressive bone flap surgery and autogenous decompressive bone flap after bone flap collection\n6. signed the informed consent.\n\nExclusion Criteria:\n\n1. Poor healing of skin flap (active infection, non-healing, necrosis, sinus, thin or poor blood supply, etc.).\n2. Fracture of bone flap ≥2 pieces, partial open fracture\n3. Intracranial infection before operation.\n4. Severe bone metabolic diseases.\n5. Long-term use of immunosuppressants.\n6. Pregnant or lactating women.\n7. Coagulation disorders.\n8. Severe cardiopulmonary insufficiency.\n9. It is estimated that the CP process cannot be completed within 6 weeks after the bone plate decompression surgery.\n10. Skull defect size less than 25cm².\n11. Life expectancy less than 1 year.\n12. mRS greater than 1 before primary disease.\n13. Diabetic patients.\n14. Patients who are unable to cooperate with follow-up assessment (e.g. mental illness).","ALL","18 Years","80 Years",{"count":142,"type":143},582,"ESTIMATED","INTERVENTIONAL",[146],"NA","To compare the neurological recovery and complication rate of autogenous cranioplasty(CP) within 6 weeks after decompressive craniectomy (DC) with that of autogenous cranioplasty within 3\\~6 months after DC.",[149],"Cranial Defect",[151,152,153,154],"Decompressive craniectomy and Cranioplasty","operation opportunity","ultra-early","Autologous skull","NOT_YET_RECRUITING","2025-09-17",{"date":158,"type":159},"2025-09-19","ACTUAL",{"date":161,"type":143},"2025-10-01",{"date":163,"type":143},"2027-09-01",{"name":5,"class":6},7]