About this trial

This trial studies health outcomes after treatment in patients with retinoblastoma. Gathering health information over time from patients and family members through vision assessments, samples of tissue and saliva, and questionnaires may help doctors learn more about what causes retinoblastoma, identify long-term health outcomes for patients with retinoblastoma, and find out which therapies may be the best for treating retinoblastoma

Eligibility criteria

Qualifiers

Unilateral or bilateral intraocular retinoblastoma

Diagnosis between the ages of 0 - 17.99 years

Diagnosis on or after January 1, 2008

No exclusions based on primary or secondary treatment modalities

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Biospecimen collection
  • Vision assessment
  • Questionnaire administration
  • Quality of life assessment
  • Laboratory Biomarker Analysis

Treatment groups

900 Participants
are divided into 2 treatment groups

Locations

11
Canada
The Hosptial for Sick Children Toronto Canada
United States
Illinois
Lurie Children's Hospital60611, Chicago United States
University of Illinois, Chicago60612, Chicago United States
Minnesota
University of Minnesoa55455, Minneapolis United States

Sponsors and collaborators

Vanderbilt-Ingram Cancer Center

Lead sponsor

National Cancer Institute (NCI)

Collaborator