Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit

ConditionsCritical Illness Intensive Care Units (ICUs)Weaning Failure Mechanical Ventilation Spontaneous Breathing Trial Diaphragm Electrical Activity Oxygen Consumption

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorLeiden University Medical Center

About this trial

The goal of this observational study is to measure effort using esophageal pressure measurements, oxygen consumption and diaphragm activity in mechanically ventilated Intensive Care Unit patients during a Spontaneous Breathing Trial. The main question aims to answer whether the sEMG signal derived from the SERA device, effort parameters and oxygen consumption have an association with weaning failure.

Participants will be measured while performing a spontaneous breathing trial.

Eligibility criteria

Qualifiers

18 years of age or older

Esophageal catheter in situ (standard of care)

Eligible for an SBT in the near future according to the LUMC SBT protocol currently valid

Disqualifiers

Severe cardiac failure NYHA class IV without mechanical support (LVAD or Impella)

COPD Gold IV

Pregnancy

Patients with ECMO

Trial design

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Locations

Leiden University Medical Centre2300 ZA, Leiden Netherlands

Sponsors and collaborators

Leiden University Medical Center

Lead sponsor

Demcon-Macawi

Collaborator

Source ClinicalTrials.gov