[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100304969":3},{"organization":4,"armGroups":7,"interventions":41,"overallOfficials":61,"centralContacts":66,"locations":73,"responsibleParty":91,"collaborators":93,"id":101,"slug":10,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":10,"eligibilityCriteria":106,"healthyVolunteers":107,"sex":108,"minAge":109,"maxAge":10,"enrollmentInfo":110,"targetDuration":10,"studyType":113,"phases":10,"briefSummary":114,"conditions":115,"keywords":120,"overallStatus":75,"whyStopped":10,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":135},{"fullName":5,"class":6},"University of Latvia","OTHER",[8,17,21,25,29,33,37],{"label":9,"type":10,"description":11,"interventionNames":12},"Gastric cancer",null,"Gastric adenocarcinoma and other gastric malignancies",[13,14,15,16],"Procedure: Upper endoscopy with biopsies","Procedure: Plasma\u002Fserum sampling","Procedure: Biopsies for gastric microbiota","Procedure: Faecal sample acquisition",{"label":18,"type":10,"description":19,"interventionNames":20},"Gastric mucosal dysplasia","Includes: a. High-grade dysplasia; b. Low-grade dysplasia; c. Indefinite for dysplasia",[13,14,15,16],{"label":22,"type":10,"description":23,"interventionNames":24},"High-risk IM gastritis stages","High-risk stages according to OLGIM classification: OLGIM Stage IV and OLGIM Stage III.",[13,14,15,16],{"label":26,"type":10,"description":27,"interventionNames":28},"High-risk atrophic gastritis stages","High-risk stages according to OLGA classification: OLGA Stage IV and OLGA Stage III.",[13,14,15,16],{"label":30,"type":10,"description":31,"interventionNames":32},"Extensive gastric intestinal metaplasia","Intestinal metaplasia of any grade both in gastric corpus and antrum\u002Fincisura (other than OLGIM III-IV).",[13,14,15,16],{"label":34,"type":10,"description":35,"interventionNames":36},"Extensive atrophy","Moderate to severe (++ or +++) atrophy both in corpus and antrum\u002Fincisura, other than OLGA III-IV.",[13,14,15,16],{"label":38,"type":10,"description":39,"interventionNames":40},"Isolated corpus atrophy","Isolated moderate-to-severe atrophy or IM in the corpus.",[13,14,15,16],[42,49,53,57],{"type":43,"name":44,"description":45,"armGroupLabels":46,"otherNames":47},"PROCEDURE","Upper endoscopy with biopsies","Upper endoscopy with proper biopsy work-up will be used for identification and stratification of gastric lesions as well as acquisition of biopsies for histopathological examination, including H.pylori detection",[34,30,9,18,22,26,38],[48],"gastroscopy, upper endoscopy",{"type":43,"name":50,"description":51,"armGroupLabels":52,"otherNames":10},"Plasma\u002Fserum sampling","Plasma\u002Fserum sampling will be used to obtain information for group stratification, e.g. H.pylori status determination, serum biomarkers",[34,30,9,18,22,26,38],{"type":43,"name":54,"description":55,"armGroupLabels":56,"otherNames":10},"Biopsies for gastric microbiota","During upper endoscopy biopsies for gastric microbiota analysis will be obtained",[34,30,9,18,22,26,38],{"type":43,"name":58,"description":59,"armGroupLabels":60,"otherNames":10},"Faecal sample acquisition","Faecal samples will be obtained for faecal occult blood testing as well as microbiota analysis",[34,30,9,18,22,26,38],[62],{"name":63,"affiliation":64,"role":65},"Marcis Leja, Prof.,PhD","Institute of Clinical and Preventive Medicine, University of Latvia","STUDY_DIRECTOR",[67],{"name":68,"role":69,"phone":70,"phoneExt":71,"email":72},"Ilze Kikuste, PhD","CONTACT","28357349","+371","ikikuste@gmail.com",[74],{"facility":5,"status":75,"city":76,"state":10,"zip":77,"country":78,"cosmosGeoPoint":79,"geoPoint":84,"contacts":85},"RECRUITING","Riga","LV 1586","Latvia",{"type":80,"coordinates":81},"Point",[82,83],24.10589,56.946,{"lat":83,"lon":82},[86,88],{"name":68,"role":69,"phone":87,"phoneExt":10,"email":72},"+317 28357349",{"name":89,"role":69,"phone":10,"phoneExt":10,"email":90},"Marcis Leja, Prof., PhD","marcis.leja@lu.lv",{"type":92,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[94,96,99],{"name":95,"class":6},"Digestive Diseases Centre GASTRO",{"name":97,"class":98},"Riga East Clinical University Hospital","OTHER_GOV",{"name":100,"class":6},"Academic Histology Laboratory (Latvia)","100304969",false,"NCT03250091","Surveillance of Patients With Precancerous Lesions of the Stomach","Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach","Inclusion Criteria:\n\nPatients undergoing upper endoscopy Motivation to participate in the study Signed consent\n\nExclusion Criteria:\n\nKnown gastric cancer Unwillingness or inability to co-operate",true,"ALL","18 Years",{"count":111,"type":112},2000,"ESTIMATED","OBSERVATIONAL","The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.",[116,117,118,119],"Gastric Cancer","Gastric Intestinal Metaplasia","Gastric Atrophy","Gastric Dysplasia",[121,122,123,124,125],"gastric precancerous lesions","gastric cancer","gastric intestinal Metaplasia","gastric atrophy","gastric dysplasia","2018-08-20",{"date":128,"type":129},"2018-08-21","ACTUAL",{"date":131,"type":129},"2017-06-19",{"date":133,"type":112},"2027-12",{"name":5,"class":6},1]