The SWEMMA trial is an open, national, multi-center, prospective, randomized (1:1), superiority trial designed to assess impact on reoperation rates for chronic subdural hematoma with a head-to-head comparison of embolization of the middle meningeal artery (intervention) with standard neurosurgical hematoma evacuation (control).
Men and women 18-89 y/o
Non-contrast Computed Tomography (NCCT)- or Magnetic Resonance Imaging (MRI)- verified, previously unoperated uni- or bilateral cSDH
Clinical and/or radiological status indicating neurosurgical treatment
Markwalder Scale score <2
Acute subdural hematoma
Focal, non-hemispheric cSDH
Midline shift >10 mm and/or effaced basal cisterns and/or significant dilatation of one or both lateral ventricle temporal horns and/or incipient uncal herniation
Structural pathology causing the cSDH (e.g. dural AV-fistula, AVM, tumor, arachnoid cyst, ventriculoperitoneal shunt)
Region Skane
Lead sponsor
Lund University
Collaborator
Sahlgrenska University Hospital
Collaborator
Karolinska University Hospital
Collaborator
Norrlands University Hospital
Collaborator