About this trial

The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory problems. SPAC aims to answer important questions on clinical phenotypes, prognosis, diagnosis and treatment. SPAC is part of routine care, and only clinically indicated investigations are done. The comprehensive baseline assessment includes a detailed questionnaire to families, plus test results, diagnoses and treatments from hospital records. Follow-up is via monthly questionnaires the first 12 months and thereafter annual questionnaires to families, and data from follow-up visits.

Currently, 4344 patients from 10 clinics and hospitals in Switzerland (Aarau, Basel, Bern, Chur, Horgen, Lausanne, Luzern, St. Gallen, Worb, Zurich) have been enrolled.

SPAC provides real-life data on children visiting the Swiss health care system for common respiratory problems. It will provide a research platform for health services research, and for nested clinical and transitional studies.

Publications and plain language summaries are listed on the study website: https://www.spac-study.ch/publikationen/

Eligibility criteria

Qualifiers

Children and adolescents aged 0-16 years

Resident in Switzerland

Seen in a paediatric pulmonary outpatient clinic due to respiratory problems

Parents and patients above age 14 must be able to sign an informed consent form

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

6,000 Participants
are grouped into 1 trial group

Locations

12
Austria
Vienna Open Medical Institute Vienna Austria
Switzerland
Children's hospital Aarau Aarau Switzerland
University Children's hospital Basel, UKBB Basel Switzerland
Institute of Social and Preventive Medicine3012, Bern Switzerland

Sponsors and collaborators

University of Bern

Lead sponsor