[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498942":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":21,"centralContacts":21,"locations":27,"responsibleParty":48,"collaborators":21,"id":50,"slug":21,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":21,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":21,"overallStatus":29,"whyStopped":21,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"University of Calgary","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All eligible participants","EXPERIMENTAL","All eligible participants are randomly assigned to one of two interventions- early Head-Up Tilt Table procedure or early Implantable Loop Recorder. The assignment is random and at a 1:1 ratio between the two strategies.\n\nInterventions:\n\nDiagnostic Test: Head Up Tilt Table (HUT) Device: Implantable Loop Recorder",[13,14],"Diagnostic Test: Diagnostic Test: Head Up Tilt Table (HUT)","Device: Device: Implantable Loop Recorder",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DIAGNOSTIC_TEST","Diagnostic Test: Head Up Tilt Table (HUT)","Participant randomized to open-label diagnostic strategy. Results and all follow-up care to be in the hands of treating cardiologist as this is a pragmatic study.\n\nthe early HUT \\[protocol: supine pre-tilt phase 5 min, un-medicated HUT to 70 degrees for 20 minutes; if response negative then 400 μg of sublingual nitroglycerin and continued 70 degree tilt for 20 minutes\\]",[9],null,{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":21},"DEVICE","Device: Implantable Loop Recorder","ILR is a small subcutaneously implanted device, lasting up to 3 years, that records heart rhythms, and which may be either auto-triggered or patientactivated.",[9],[28],{"facility":5,"status":29,"city":30,"state":31,"zip":32,"country":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"RECRUITING","Calgary","Alberta","T2N 4Z6","Canada",{"type":35,"coordinates":36},"Point",[37,38],-114.08529,51.05011,{"lat":38,"lon":37},[41,46],{"name":42,"role":43,"phone":44,"phoneExt":21,"email":45},"Dr. Robert S Sheldon, MD, PhD","CONTACT","403-220-8191","sheldon@ucalgary.ca",{"name":47,"role":43,"phone":21,"phoneExt":21,"email":21},"Dr. Robert S Sheldon, MD PhD",{"type":49,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100498942",false,"NCT05776810","Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial","Syncope Trial to Understand Tilt Testing or ECG Recording. Tenth Prevention of Syncope","(POST10)","Inclusion Criteria:\n\n* age \\>50 years old\n* ≥1 syncope26 in the prior 12 months\n* diagnosis unclear after history, physical exam, and electrocardiogram\n* no apparent risk of death due to the cause of syncope\n\nExclusion Criteria:\n\n* cannot provide informed consent or attend routine follow up\n* have known left ventricular ejection fraction \\\u003C 50%,or have\n* pacemaker, ICD, or ICM\n* Class I indication for permanent pacing or ICD implantation\n* hypertrophic cardiomyopathy\n* a history of myocardial infarction within 3 months prior to enrolment\n* a major chronic co-morbid medical condition that would preclude 12 months of follow-up\n* bifascicular block\n* epilepsy proven by electroencephalography\n* syncope of known cause","ALL","50 Years","110 Years",{"count":61,"type":62},144,"ESTIMATED","INTERVENTIONAL",[65],"NA","The Study To Understand Tilt Tests versus Extended Recordings (STUTTER, POST 10) will test the hypothesis that first performing a diagnostic HUT in older patients with syncope of unknown cause will provide earlier and more diagnoses than inserting an ICM.",[68],"Syncope","2024-12-16",{"date":71,"type":72},"2024-12-19","ACTUAL",{"date":74,"type":72},"2023-05-01",{"date":76,"type":62},"2026-12-31",{"name":5,"class":6},1]