[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567532":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":54,"collaborators":12,"id":56,"slug":12,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":12,"enrollmentInfo":65,"targetDuration":12,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":43,"whyStopped":12,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control\u002FUsual Care","NO_INTERVENTION","Chemotherapy infusion clinics deliver infusion services based on the American Society of Clinical Oncology (ASCO) Quality Oncology Practice Initiative (QOPI) Chemotherapy Administration Safety Standards (2020) including standard toxicity screening and providing standard chemotherapy patient education with general information for managing nausea and other gastrointestinal side effects and nutrition tips. Usual care patients will be supplemented with a single-item question to evaluate taste alteration severity and to gather information about what they are doing and their diet intake.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Treatment - TA Self-monitoring and Self-management","EXPERIMENTAL","The nurse-led intervention involves using a valid\u002Freliable TA assessment tool (Chemotherapy-induced Taste Alterations Scale (CiTAS) and teaching the patient to use the assessments and the evidence-based Patient Education Sheet to select assessment-driven interventions to manage TA symptoms. Data is collected about the specific actions prescribed in the teaching tool to identify which interventions were used and their overall impact.",[18,19],"Behavioral: Taste Alteration Self-Assessment","Behavioral: Taste Alternation Self-Management",[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":12},"BEHAVIORAL","Taste Alteration Self-Assessment","The nurse-led intervention involves using a valid\u002Freliable TA assessment tool (Chemotherapy-induced Taste Alterations Scale (CiTAS) and teaching the patient to select assessment-driven interventions to manage TA symptoms.",[14],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":12},"Taste Alternation Self-Management","The nurse-led intervention involves teaching the patient to use the assessments and the evidence-based Patient Education Sheet to select assessment-driven interventions to manage their symptoms. Data will be collected about the specific actions prescribed in the teaching tool and to identify which interventions were used and their overall impact.",[14],[31],{"name":32,"affiliation":33,"role":34},"Mary L Hook, PhD, RN","Aurora Sinai Medical Center","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":12,"email":39},"CONTACT","414-218-0990","mary.hook@aah.org",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":12},"Advocate Illinois Masonic Medical Center","RECRUITING","Chicago","Illinois","60657","United States",{"type":49,"coordinates":50},"Point",[51,52],-87.65005,41.85003,{"lat":52,"lon":51},{"type":55,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100567532",false,"NCT06669416","Taste Alterations Study","Effects of Patient Education and Self-Management in Cancer Patients Who Experience Chemotherapy-Induced Taste Alterations","TAS","Inclusion Criteria:\n\n* Medical diagnosis of cancer with types limited to the top cancer types \\[Note: Cancer types that are rare will be excluded\\]\n* Initiating chemotherapy (first day\u002Ffirst cycle) at participating clinics\n* English speaking\u002Freading (without an interpreter)\n\nExclusion Criteria:\n\n* Substitute decision-maker (activated)\n* History of head\u002Fneck cancer or irradiation\n* Known genetic\u002Fmetabolic disorder impacting taste (preexisting dysgeusia)\n* Known eating disorder\n* Receiving enteral or parenteral nutrition (special nutritional needs)\n* Pregnant women (unique needs)\n* Patients with medical orders for end of life\u002Fhospice care","ALL","18 Years",{"count":66,"type":67},400,"ESTIMATED","INTERVENTIONAL",[70],"NA","The main questions it aims to answer are:\n\n1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any patterns in TA symptom occurrence based on age, sex, race\u002Fethnicity, cancer type, chemotherapy agent, etc.\n2. Do patients take action to deal with the TA? What strategies are used? Do patients in the intervention group use the assessments to select interventions?\n3. Do the interventions lessen TA symptoms and maintain food intake? Is the treatment (in-depth assessment and education) more effective in lessening the intensity of TA than usual care? Which level of assessment is needed to support symptom management to reduce symptom severity?\n\nParticipants will:\n\nComplete baseline assessment before starting their initial chemotherapy infusion (all patients) Participate in baseline patient education based on assigned intervention (usual care vs. treatment) Engage in TA management between chemotherapy infusion clinic visits based on education Visit the clinic for chemotherapy infusions as scheduled; Complete TA assessments and reporting based on intervention; Work with nurse coaches to answer questions and help with the intervention.\n\nComplete study data collection on the 4th chemotherapy cycle (but continue intervention) Complete final data collection at 6 months",[73,74],"Chemotherapy Side Effects","Taste, Altered",[76,77],"self-management","cluster randomized control trial","2026-05-20",{"date":80,"type":81},"2026-05-22","ACTUAL",{"date":83,"type":81},"2024-12-01",{"date":85,"type":67},"2026-09",{"name":5,"class":6},1]