[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100473051":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":48,"collaborators":10,"id":52,"slug":10,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"TAVR in aortic valve disease",null,[12],"Device: transcatheter heart valve",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","transcatheter heart valve","patients with severe aortic valve disease underwent transcatheter heart valve",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Jun-Jie Zhang, MD","CONTACT","+86-25-52271350","jameszll@163.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Jing Kan, MPH","+86-25-52271398","kanjingok@126.com",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Nanjing First Hospital","RECRUITING","Nanjing","Jiangsu","210006","China",{"type":38,"coordinates":39},"Point",[40,41],118.77778,32.06167,{"lat":41,"lon":40},[44],{"name":45,"role":22,"phone":46,"phoneExt":10,"email":47},"Shao-Liang Chen","+86 13605157029","chmengx@126.com",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Junjie Zhang","Vice chief","100473051",false,"NCT05439863","TAVR for Aortic Valve Disease","Transcatheter Aortic Valve Replacement for Severe Aortic Valve Disease: Multi-center, Real-word Registry","Inclusion Criteria:\n\n1. Clinical diagnosis of severe aortic stenosis or aortic regurgitation\n2. Patients undergo transcatheter aortic valve replacement\n\nExclusion Criteria:\n\npatients refuse the clinical follow-up","ALL","18 Years",{"count":61,"type":62},5000,"ESTIMATED","15 Years","OBSERVATIONAL","Transcatheter aortic valve replacement (TAVR) has became an important treatment of severe aortic stenosis (AS). Several randomized clinical trials showed that TAVR was non-inferior or superior to surgical aortic valve replacement (SAVR). However, many different issues have emerged: TAVR in younger patients? valve leaflet thrombosis? transcatheter valve durability? coronary reaccess after TAVR? TAVR in bicuspid aortic valve? TAVR in aortic regurgitation? etc. Hence, a prospective, multicenter database is created to provide the real-word data for these questions.",[67],"Aortic Valve Disease","2024-11-13",{"date":70,"type":71},"2024-11-15","ACTUAL",{"date":73,"type":71},"2022-07-01",{"date":75,"type":62},"2037-12-30",{"name":5,"class":6},1]