[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634108":3},{"organization":4,"outcomesModule":7,"designInfo":36,"detailedDescription":43,"studyPopulation":35,"armGroups":44,"interventions":57,"overallOfficials":67,"centralContacts":71,"locations":77,"responsibleParty":92,"collaborators":96,"id":99,"slug":35,"hasResults":100,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":35,"eligibilityCriteria":104,"healthyVolunteers":100,"sex":105,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":35,"studyType":111,"phases":112,"briefSummary":114,"conditions":115,"keywords":117,"overallStatus":80,"whyStopped":35,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Marmara University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":35},[9,13],{"measure":10,"description":11,"timeFrame":12},"Exercise Capacity","Change in 6-minute walk distance assessed by the 6-minute walk test to evaluate functional capacity.","Baseline and at 8 weeks",{"measure":14,"description":15,"timeFrame":12},"Dyspnea severity measured by the Modified Borg Dyspnea Scale","Change in dyspnea severity assessed using the Modified Borg Dyspnea Scale. The Modified Borg Dyspnea Scale is a subjective rating scale used to assess the severity of dyspnea at rest and\u002For during activity. Scores range from 0 to 10, with higher scores indicating greater dyspnea severity and a worse outcome.",[17,20,23,26,29,32],{"measure":18,"description":19,"timeFrame":12},"Fatigue severity measured by the Fatigue Severity Scale","Change in fatigue severity assessed using the Fatigue Severity Scale. The Fatigue Severity Scale is a 9-item patient-reported outcome measure assessing the severity and impact of fatigue. Each item is scored from 1 to 7. Total score can be calculated as the sum of all items, ranging from 9 to 63, or as the mean item score, ranging from 1 to 7. Higher scores indicate greater fatigue severity and a worse outcome.",{"measure":21,"description":22,"timeFrame":12},"Physical activity level","Change in physical activity level assessed using the International Physical Activity Questionnaire-Short Form.",{"measure":24,"description":25,"timeFrame":12},"Anxiety and depression measured by the Hospital Anxiety and Depression Scale","Change in anxiety and depression levellevel assessed using the Hospital Anxiety and Depression Scale. The Hospital Anxiety and Depression Scale is a 14-item self-report questionnaire developed to assess psychological distress in patients with physical health problems. It consists of 2 subscales, anxiety and depression, with 7 items in each subscale. Each item is scored from 0 to 3. Total scores range from 0 to 42, with higher scores indicating worse psychological status and a worse outcome.",{"measure":27,"description":28,"timeFrame":12},"Pulmonary function parameters","Change in pulmonary function parameters including forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1\u002FFVC ratio.",{"measure":30,"description":31,"timeFrame":12},"Quality of life measured by the Short Form-36 (SF-36)","Change in health-related quality of life assessed using the Short Form-36 questionnaire. The 36-Item Short Form Survey (SF-36) is a validated self-report questionnaire used to assess health-related quality of life. It includes 8 domains: physical functioning, bodily pain, general health perception, role limitations due to physical problems, role limitations due to emotional problems, social functioning, mental health, and vitality. Scores range from 0 to 100, with higher scores indicating better health-related quality of life and a better outcome.",{"measure":33,"description":34,"timeFrame":12},"Independence in activities of daily living measured by the Barthel Index","Change in functional independence in activities of daily living assessed using the Barthel Index. The Barthel Index is a standardized measure used to assess independence in activities of daily living. Scores range from 0 to 100, with higher scores indicating greater independence in daily activities and a better outcome. A score of 100 indicates full independence, while lower scores indicate increasing levels of dependency.",null,{"allocation":37,"interventionModel":38,"interventionModelDescription":39,"primaryPurpose":40,"observationalModel":35,"timePerspective":35,"maskingInfo":41},"RANDOMIZED","PARALLEL","Participants will be randomly assigned to either a synchronous telerehabilitation group or a control group. The synchronous telerehabilitation group will receive aerobic, endurance, and strengthening exercises, while the control group will perform breathing and posture exercises. Both groups will participate in the program 3 days per week, 30 minutes per session, for 8 weeks.","TREATMENT",{"masking":42,"maskingDescription":35,"whoMasked":35},"NONE","Pulmonary hypertension is associated with impaired cardiopulmonary function, reduced aerobic capacity, decreased oxygen consumption, and exercise intolerance. Dyspnea, fatigue, reduced physical activity, and limitations in daily activities negatively affect functional status, psychological well-being, and quality of life in this patient population. Exercise-based rehabilitation has been reported to improve functional capacity, exercise performance, and overall well-being in patients with pulmonary vascular disease, despite earlier concerns that exercise might worsen symptoms in these patients.\n\nTelerehabilitation refers to the delivery of rehabilitation services through telecommunication technologies. Synchronous telerehabilitation is based on real-time interaction between the clinician and the patient and may be a useful, accessible, and safe alternative when attendance at center-based rehabilitation is difficult. Previous studies have shown beneficial effects of exercise-based telerehabilitation in cardiopulmonary populations; however, evidence regarding synchronous telerehabilitation in patients with elevated pulmonary artery pressure remains limited.\n\nThe aim of this study is to investigate the effectiveness of a synchronous telerehabilitation program in patients with elevated pulmonary artery pressure identified by echocardiography, defined as systolic pulmonary artery pressure (sPAP) of 50 mmHg or higher. Participants will be randomly assigned to either a synchronous telerehabilitation group or a control group. The telerehabilitation group will receive a supervised program including aerobic, endurance, and strengthening exercises, while the control group will perform breathing and posture exercises. Both groups will participate in the program 3 days per week, 30 minutes per session, for 8 weeks. At the end of the 8-week period, participants in the control group who wish to continue may be offered the synchronous rehabilitation program.\n\nThe study will evaluate the effects of the intervention on cardiopulmonary and functional outcomes, including dyspnea, fatigue, physical activity level, psychological status, pulmonary function, exercise capacity, functional capacity, and quality of life. Assessments will be performed before and after the intervention period using standardized outcome measures.\n\nThe findings of this study may help clarify the role of synchronous telerehabilitation as an accessible rehabilitation strategy for patients with elevated pulmonary artery pressure, particularly for individuals who have difficulty accessing in-person rehabilitation services. Given the limited evidence in this specific population, this study is expected to contribute clinically relevant data regarding the effectiveness of remote exercise-based rehabilitation.",[45,51],{"label":46,"type":47,"description":48,"interventionNames":49},"Synchronous Telerehabilitation Group","EXPERIMENTAL","Participants with elevated pulmonary artery pressure identified by echocardiography (systolic pulmonary artery pressure ≥50 mmHg) who meet the study eligibility criteria will receive an 8-week synchronous telerehabilitation program. The program will be delivered 3 days per week, 30 minutes per session, under real-time physiotherapist supervision. The intervention will include aerobic, endurance, and strengthening exercises. Exercise intensity and progression will be individualized according to clinical status, baseline adaptation, and cardiopulmonary exercise test findings. Hemodynamic parameters, oxygen saturation, dyspnea, and fatigue will be monitored during sessions.",[50],"Behavioral: Synchronous Telerehabilitation",{"label":52,"type":53,"description":54,"interventionNames":55},"Control Group","ACTIVE_COMPARATOR","Participants with elevated pulmonary artery pressure identified by echocardiography (systolic pulmonary artery pressure ≥50 mmHg) who meet the study eligibility criteria will perform breathing and posture exercises for 8 weeks. Participants in this group will continue routine care and receive weekly motivational follow-up by a physiotherapist. At the end of the study period, participants in the control group may be offered the exercise program if they wish to continue.",[56],"Behavioral: Breathing and Posture Exercises",[58,63],{"type":59,"name":60,"description":61,"armGroupLabels":62,"otherNames":35},"BEHAVIORAL","Synchronous Telerehabilitation","A supervised synchronous telerehabilitation program delivered via videoconferencing, including aerobic, endurance, and strengthening exercises for 8 weeks, 3 times per week, 30 minutes per session. The program will be individualized based on participant tolerance and clinical findings, with monitoring of symptoms and physiologic responses during exercise.",[46],{"type":59,"name":64,"description":65,"armGroupLabels":66,"otherNames":35},"Breathing and Posture Exercises","A control intervention consisting of breathing exercises, positions to relieve breathing discomfort, breathing control techniques, energy conservation strategies, and posture exercises, performed for 8 weeks, together with routine care and weekly motivational follow-up.",[52],[68],{"name":69,"affiliation":5,"role":70},"Aysel Yıldız Özer, PhD","STUDY_DIRECTOR",[72],{"name":73,"role":74,"phone":75,"phoneExt":35,"email":76},"Mehmet Armağan Physiotherapist, Msc","CONTACT","00903562521616","mehmetarm@gmail.com",[78],{"facility":79,"status":80,"city":81,"state":35,"zip":35,"country":82,"countryCode":35,"cosmosGeoPoint":83,"geoPoint":88,"contacts":89},"Tokat Gaziosmanpaşa University","RECRUITING","Tokat Province","Turkey (Türkiye)",{"type":84,"coordinates":85},"Point",[86,87],36.55444,40.31389,{"lat":87,"lon":86},[90],{"name":91,"role":74,"phone":75,"phoneExt":35,"email":76},"Mehmet Armağan",{"type":93,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Aysel Yildiz","Professor",[97],{"name":98,"class":6},"Tokat Gaziosmanpasa University","100634108",false,"NCT07535398","Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure","The Effectiveness of Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n* Elevated pulmonary artery pressure identified by echocardiography, defined as systolic pulmonary artery pressure (sPAP) of 50 mmHg or higher\n* Clinically stable and receiving medical treatment under cardiology follow-up World Health Organization functional class I or II\n* New York Heart Association (NYHA) functional class I or II\n* Living with a caregiver, family member, or another person who can provide assistance if needed\n* Access to the internet and adequate visual, cognitive, and functional ability to participate in videoconference-based sessions\n* Willing to participate and able to provide informed consent\n\nExclusion Criteria:\n\n* Requirement for oxygen therapy\n* Musculoskeletal problems limiting participation in exercise\n* Ongoing treatment for psychiatric or psychological disorders\n* Cognitive impairment based on Mini-Mental State Examination findings\n* Severe chronic obstructive pulmonary disease (COPD)\n* Other significant cardiac disease that may interfere with participation or assessment","ALL","18 Years","65 Years",{"count":109,"type":110},12,"ESTIMATED","INTERVENTIONAL",[113],"NA","The goal of this clinical trial is to learn if synchronous telerehabilitation is effective in patients with elevated pulmonary artery pressure identified by echocardiography (systolic pulmonary artery pressure ≥50 mmHg). It will also evaluate the effects of telerehabilitation on exercise capacity, dyspnea, fatigue, functional status, and quality of life. The main questions it aims to answer are:\n\nDoes synchronous telerehabilitation improve exercise and functional capacity in these patients? Does synchronous telerehabilitation improve dyspnea, fatigue, psychological status, and quality of life?\n\nResearchers will compare synchronous telerehabilitation with breathing and posture exercises to see if telerehabilitation provides greater clinical and functional benefit.\n\nParticipants will:\n\nBe randomly assigned to one of 2 groups Follow an 8-week program, 3 times per week, for 30 minutes per session Perform aerobic, endurance, and strengthening exercises by synchronous telerehabilitation, or breathing and posture exercises in the control group Complete assessments before and after treatment",[116],"Elevated Pulmonary Artery Pressure",[118,119,120,121,122,123],"Elevated pulmonary artery pressure","pulmonary hypertension","synchronous telerehabilitation","exercise capacity","pulmonary function","quality of life","2026-04-27",{"date":126,"type":127},"2026-04-29","ACTUAL",{"date":129,"type":110},"2026-04",{"date":131,"type":110},"2026-08",{"name":5,"class":6},1]