About this trial

Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their survival has significantly improved, but their brain insult has not been paid much attention. This study is to determine the relationship between specific proteins in the blood and brain injury in patients less than 18-year-old undergoing heart surgery.

Eligibility criteria

Qualifiers

less than 18 years old

undergoing cardiac surgery with cardiopulmonary bypass at Boston Children's Hospital

Disqualifiers

undergoing an emergent procedure and do not have more than 1 hour ahead of time to review the consent

patient in a moribund condition American Society of Anesthesiology (ASA 5)

patient with a hematological and/or oncological disease

Jehovah witnesses

Trial design

Treatments tested in this trial

  • Collecting discarded blood samples

Treatment groups

100 Participants
are divided into 1 treatment group

Locations

1
Boston Children's Hospital02115, BostonMassachusetts, United States

Sponsors and collaborators

Boston Children's Hospital

Lead sponsor