[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592269":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":42,"responsibleParty":54,"collaborators":26,"id":56,"slug":26,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":26,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":26,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Total knee arthroplasty (TKA) + Cryoablation","EXPERIMENTAL","Patients will receive cryoablation during the two to three weeks prior to the TKA procedure.",[13,14],"Procedure: Total knee arthroplasty (TKA)","Device: Cryoablation",{"label":16,"type":17,"description":18,"interventionNames":19},"TKA Only","ACTIVE_COMPARATOR","Patients will NOT receive cryoablation prior to the TKA procedure.",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Total knee arthroplasty (TKA)","Administered as part of patient standard of care.",[16,9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DEVICE","Cryoablation","Cryoablation will be administered on the leg of the knee indicated for surgery.",[9],[33],{"name":34,"affiliation":5,"role":35},"Joshua Rozell, MD","PRINCIPAL_INVESTIGATOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Daniel Waren","CONTACT","212-598-6245","Daniel.waren@nyulangone.org",[43],{"facility":5,"status":44,"city":45,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":26},"RECRUITING","New York","10016","United States",{"type":49,"coordinates":50},"Point",[51,52],-74.00597,40.71427,{"lat":52,"lon":51},{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100592269",false,"NCT06991231","The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty","The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty - A Randomized Prospective Clinical Trial","Inclusion Criteria:\n\n* Patients are candidates for elective primary total knee arthroplasty for a diagnosis of osteoarthritis or inflammatory arthritis.\n* Patients have been medically cleared and scheduled for surgery\n\nExclusion Criteria:\n\n* Patients with cold-related conditions (cryoglobulinemia, paroxysmal cold hemoglobinuria, cold urticaria, and Raynaud's disease)\n* Surgery for fracture, infection, or malignancy","ALL","18 Years",{"count":65,"type":66},215,"ESTIMATED","INTERVENTIONAL",[69],"NA","The purpose of this study is to evaluate the efficacy of cryoablation use on patient-reported outcomes (PROMs) and opioid consumption following total knee arthroplasty. This is a randomized study that will involve a 1:1 randomization to total knee arthroplasty +\u002F- cryoablation.",[72,73],"Post-Operative Pain","Total Knee Arthroplasty","2026-03-30",{"date":76,"type":77},"2026-04-03","ACTUAL",{"date":79,"type":77},"2025-06-13",{"date":81,"type":66},"2027-01-01",{"name":5,"class":6},1]