About this trial

Vaping is increasingly popular with both adolescent and adult Canadians, but the long-term health impacts remain unknown. We believe that the tools we currently have to detect lung disease in people who vape may be insufficient and propose new ways to find lung injuries that may impact them over the course of their lives. These include exercise testing, new imaging techniques, and new breathing tests that will demonstrate how vaping may harm their lungs. We will use these tools in both adolescent and adult Canadians to give Canadians who vape important information on the consequences of vaping.

Eligibility criteria

Qualifiers

Aged ≥12 and <19 years old

Either 1) use neither combustible cigarettes nor e-cigarettes or 2) use e-cigarettes exclusively

Aged ≥19 years old

Fall into one of the following categories: 1) use neither combustible cigarettes nor e-cigarettes; 2) use combustible cigarettes exclusively, never using e-cigarettes; 3) use e-cigarettes exclusively, never using combustible cigarettes; or 4) use both combustible cigarettes and e-cigarettes currently

Disqualifiers

Contraindication to pulmonary function testing and cardiopulmonary exercise testing

Have smoked combustible cannabis within the last month and/or have a combustible cannabis smoking history of >1 joint-year

Have smoked combustible cigarettes within the last 6 months

Have a physician-diagnosed chronic lung disease (such as asthma, cystic fibrosis, or bronchopulmonary dysplasia)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

500 Participants
are grouped into 2 trial groups

Locations

8
University of Alberta (Clinical Sciences Building)T6G 2B7, EdmontonAlberta, Canada
BC Cancer AgencyV5Z 4E6, VancouverBritish Columbia, Canada
BC Children's Hospital Research InstituteV6H 3N1, VancouverBritish Columbia, Canada
St. Paul's HospitalV6Z 1Y6, VancouverBritish Columbia, Canada

Sponsors and collaborators

University of British Columbia

Lead sponsor

BC Children's Hospital Research Institute

Collaborator

Providence Healthcare

Collaborator

British Columbia Cancer Agency

Collaborator

University of Alberta

Collaborator

McMaster University

Collaborator

University of Ottawa

Collaborator

Université de Sherbrooke

Collaborator

University of Toronto

Collaborator