[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513411":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":18,"locations":28,"responsibleParty":51,"collaborators":7,"id":54,"slug":7,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":7,"enrollmentInfo":63,"targetDuration":7,"studyType":66,"phases":7,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":31,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Sample of Blood","All participants will receive M-protein screening by serum electrophoresis. Individuals with detected M-protein will undergo further diagnostic tests to determine their accurate diagnosis. Patients with monoclonal gammopathy of undetermined significance (MGUS) would be carefully assessed and followed up.",[14],{"name":15,"affiliation":16,"role":17},"Peng Liu, PhD, MD","Fudan University","PRINCIPAL_INVESTIGATOR",[19,24],{"name":15,"role":20,"phone":21,"phoneExt":22,"email":23},"CONTACT","+8621-64041990","2925","liu.peng@zs-hospital.sh.cn",{"name":25,"role":20,"phone":21,"phoneExt":26,"email":27},"Jing Li, MD","2025","li.jing6@zs-hospital.sh.cn",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Zhongshan Hospital，Fudan University","RECRUITING","Shanghai","Shanghai Municipality","200032","China",{"type":37,"coordinates":38},"Point",[39,40],121.45806,31.22222,{"lat":40,"lon":39},[43,46,48,49],{"name":44,"role":20,"phone":45,"phoneExt":22,"email":23},"Peng Liu, Ph.D","+862164041990",{"name":47,"role":20,"phone":45,"phoneExt":26,"email":27},"Jing Li, M.D.",{"name":44,"role":17,"phone":7,"phoneExt":7,"email":7},{"name":47,"role":50,"phone":7,"phoneExt":7,"email":7},"SUB_INVESTIGATOR",{"type":17,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Peng Liu","Head of Department of Hematology","100513411",false,"NCT05965115","The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study","The China Monoclonal Gammopathy Screening Project in First-degree Relatives of Patients With Multiple Myeloma (CHAPERONE) --A Multicenter Observational Study","CHAPERONE","Inclusion Criteria:\n\n1. Male or female over the age of 18;\n2. First-degree relatives (including parents, children, and biological siblings) have multiple myeloma diagnosed by the International Myeloma Working Group (IMWG) Myeloma Diagnostic Criteria;\n3. Understand the purpose and procedure of this trial and voluntarily participate in this screening study;\n4. Participants should be willing and able to follow the study follow-up plan and other protocol requirements.\n\nExclusion Criteria:\n\nPatients with a known diagnosis of plasma cell diseases, such as MGUS, smoldering myeloma (SMM), or multiple myeloma","ALL","18 Years",{"count":64,"type":65},10000,"ESTIMATED","OBSERVATIONAL","The goal of the China Monoclonal Gammopathy Screening Project in First-degree Relatives of Patients With Multiple Myeloma (CHAPERONE) study is to assess the clinical significance of screening for monoclonal gammopathy (M-protein) in first-degree relatives of patients with multiple myeloma in China population, and establish a prospective cohort of individuals with monoclonal gammopathy of undetermined significance (MGUS), a precursor conditions to multiple myeloma. We will study these patients as a means to identify risk factors for progression to symptomatic multiple myeloma.",[69,70],"Multiple Myeloma","Monoclonal Gammopathy of Undetermined Significance",[70,69,72],"Early Tumor Screening","2023-07-31",{"date":75,"type":76},"2023-08-01","ACTUAL",{"date":78,"type":65},"2023-07",{"date":80,"type":65},"2035-08",{"name":5,"class":6},1]