About this trial
Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.
Eligibility criteria
Qualifiers
RA diagnosed by a rheumatologist
Age 40- 79
≥1 ASCVD risk factor including prediabetes, hypertension, BMI >30, current or history of cigarette smoking
Disqualifiers
Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
Patients with diabetes mellitus
Pregnancy
Trial design
Treatments tested in this trial
- high sensitivity cardiac troponin
Treatment groups
Locations
1Sponsors and collaborators
Brigham and Women's Hospital
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborator