About this trial

1\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, surgical drain, and cyanoacrylate tissue adhesive, which are commonly used in oral surgery practice. The study aims to scientifically evaluate the effects of each method on patients and to determine the most appropriate clinical approach.

Eligibility criteria

Qualifiers

Patients aged 18-40 years.

Patients with no systemic diseases (ASA I).

Patients with impacted mandibular third molars indicated for extraction, with bone and/or mucosal retention, in similar positions (Pell & Gregory Class 2, Position B; Winter classification vertical or mesioangular).

Disqualifiers

Patients classified as ASA II, III, or IV.

Known allergy to anesthetic solutions.

Allergy to acrylate.

Pregnant or breastfeeding women.

Trial design

Treatments tested in this trial

  • Conventional Suturing
  • Sutureless Technique
  • Surgical Drain
  • Cyanoacrylate Tissue Adhesive

Treatment groups

148 Participants
are divided into 4 treatment groups

Locations

1
Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery RizeRize Province, Turkey (Türkiye)

Sponsors and collaborators

Recep Tayyip Erdogan University

Lead sponsor