The Effect of Virtual Reality Applications on Upper Extremity Functions in Patients With Duchenne Muscular Dystrophy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age7-18
SponsorIstanbul University

About this trial

This study aims to evaluate the effects of fully immersive virtual reality (VR) applications on upper extremity (UE) functions in individuals diagnosed with Duchenne Muscular Dystrophy (DMD). DMD is a progressive neuromuscular disorder that leads to muscle weakness and loss of function, including the upper limbs, which are essential for daily activities and independence.

In this randomized controlled trial, 36 participants with DMD will be divided into two groups: a control group receiving conventional physiotherapy and an intervention group receiving the same physiotherapy program (excluding upper extremity exercises) combined with VR-based exercises. The VR games will be designed specifically to improve shoulder, elbow, wrist, and hand functions and will be delivered using Meta Quest 3 headsets with hand-tracking capabilities.

Both groups will receive therapy twice a week for 8 weeks. Assessments will be conducted before and after the intervention, and at follow-up, using validated tools to measure UE function, grip strength, fine motor skills, trunk control, fatigue, quality of life, and participation in daily activities.

The study aims to explore innovative rehabilitation strategies for DMD and contribute to improving the independence and quality of life of affected individuals.

Eligibility criteria

Qualifiers

Clinical diagnosis of Duchenne Muscular Dystrophy (DMD)

Age ≥ 7 years

Ambulatory or non-ambulatory status (both are eligible)

Ability to follow movement instructions

Disqualifiers

Presence of any neurological diagnosis other than DMD

Cognitive, behavioral, or communication impairments that limit participation

Systemic illness or condition interfering with participation

Severe visual impairments incompatible with VR headset use

Trial design

Treatments tested in this trial

  • Virtual Reality + Conventional Physiotherapy
  • Conventional Physiotherapy
  • Formative Usability Evaluation of the VR Rehabilitation Platform

Treatment groups

36 Participants
are divided into 2 treatment groups

Locations

1
İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi34098, IstanbulFatih, Turkey (Türkiye)

Sponsors and collaborators

Istanbul University

Lead sponsor

Istanbul University - Cerrahpasa

Sponsor institution