[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641706":3},{"organization":4,"outcomesModule":7,"designInfo":22,"detailedDescription":30,"studyPopulation":21,"armGroups":31,"interventions":43,"overallOfficials":48,"centralContacts":52,"locations":21,"responsibleParty":57,"collaborators":21,"id":59,"slug":21,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":21,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":21,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":79,"whyStopped":21,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":21},{"fullName":5,"class":6},"Arizona State University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":21},[9,13],{"measure":10,"description":11,"timeFrame":12},"heart rate variability","the measure of the variation in time between consecutive heartbeats","3 minutes",{"measure":14,"description":15,"timeFrame":12},"cognitive performance","Trail making test that measures cognitive flexibility, visual attention, and executive function, with interpretation based on completion times (in seconds)",[17,19],{"measure":14,"description":18,"timeFrame":12},"Stroop Color-Word Test which measures attention span, reaction time, and ability to resist distractions",{"measure":14,"description":20,"timeFrame":12},"reaction time: measured by the elapsed time between stimulus onset and an individual's response",null,{"allocation":23,"interventionModel":24,"interventionModelDescription":25,"primaryPurpose":26,"observationalModel":21,"timePerspective":21,"maskingInfo":27},"RANDOMIZED","CROSSOVER","This is a crossover study and all participants will receive both treatments one week apart in randomized order.","BASIC_SCIENCE",{"masking":28,"maskingDescription":29,"whoMasked":21},"NONE","Masking water temperature is not possible.","Heart rate variability (HRV) is a widely recognized physiological marker that reflects the dynamic interaction between the cardiovascular and autonomic nervous systems. HRV represents millisecond-level fluctuations in time between consecutive heartbeats. It is a key indicator of autonomic nervous system balance, with higher values indicate better recovery, fitness, and stress resilience. Previous research has shown that HRV decreases under mental workload, including during tasks that require attention, inhibition, or executive function.1-3 Studies also show that temperature exposure affects autonomic regulation: cold increases sympathetic drive, while warm water supports parasympathetic activation.4-6 Very few studies combine thermal exposure with cognitive testing, and no controlled trials have investigated whether water temperature modulates HRV responses specifically during cognitive demand.",[32,38],{"label":33,"type":34,"description":35,"interventionNames":36},"Warm water","EXPERIMENTAL","Water will be heated to \\~55º C (131 ºF)",[37],"Other: water",{"label":39,"type":40,"description":41,"interventionNames":42},"Cold water","PLACEBO_COMPARATOR","Cold water: 4-6º C (41ºF)",[37],[44],{"type":6,"name":45,"description":46,"armGroupLabels":47,"otherNames":21},"water","water temperature",[39,33],[49],{"name":50,"affiliation":5,"role":51},"Carol Johnston","PRINCIPAL_INVESTIGATOR",[53],{"name":50,"role":54,"phone":55,"phoneExt":21,"email":56},"CONTACT","6024963463","carol.johnston@asu.edu",{"type":51,"investigatorFullName":50,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Professor and Senior Associate Dean","100641706",false,"NCT07654270","The Effect of Water Temperature on Heart Rate Variability and Cognition","Effects of Water Temperature on Heart Rate Variability During Cognitive Testing in Healthy Adult Women: A Randomized Crossover Trial","Inclusion Criteria:\n\n* Healthy women free of chronic disease (by self-report)\n* 18-30 years of age\n\nExclusion Criteria:\n\n* medication\u002Fdrug use that has not been consistent for the previous 3 months or will be discontinued during the trial\n* any acute illness\n* regular use of cigarettes or marijuana\n* pregnant or lactating women\n* not fluent in English\n* not willing to attend two in-person lab visits in downtown Phoenix and follow study protocol (including abstaining from caffeine in the 12 hours prior to testing)\n* not currently competing in sports or unusually high-intensity exercise protocols (e.g., high-intensity exercise greater than 30 minutes most days of the week)",true,"FEMALE","18 Years","30 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","Heart rate variability (HRV) is a key indicator of fitness, and stress resilience. Previous research has shown that HRV decreases under mental workload, including during tasks that require strict attention. Studies also show that temperature exposure affects attention: cold increases the stress response while warm water has a calming effect. Very few studies combine thermal exposure with cognitive testing, and no controlled trials have investigated whether water temperature modulates HRV responses specifically during cognitive demand.",[77],"Mental Acuity",[10,46,14],"NOT_YET_RECRUITING","2026-06-12",{"date":82,"type":83},"2026-06-17","ACTUAL",{"date":85,"type":71},"2026-07-13",{"date":87,"type":71},"2027-06-15",{"name":5,"class":6}]