[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617909":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":63,"collaborators":26,"id":66,"slug":26,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":26,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":86,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Middlesex University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Treatment","EXPERIMENTAL","Dietary supplement containing standardised herbal extracts of Boswellia Serrata (525 mg), Curcuma Longa (150 mg), Vitis vinifera (75 mg)",[13],"Dietary Supplement: Active treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Dietary supplement placebo containing no standardised herbal extracts or other active ingredients.",[19],"Other: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Active treatment","A dietary supplement containing standardised herbal extracts of Boswellia serrata (525 mg), Curcuma longa (150 mg), Vitis vinifera (75 mg). Four times a day.",[9],null,{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"A placebo containing no standardised herbal extracts or other active ingredients. Four times a day.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Patrycja Brodka Pedrp, MSc","CONTACT","020-8411-2721","p.x.brodkapedro@mdx.ac.uk",{"name":37,"role":33,"phone":38,"phoneExt":26,"email":39},"Lygeri Dimitriou, Dr","020-8411-4354","l.dimitriou@mdx.ac.uk",[41],{"facility":42,"status":43,"city":44,"state":26,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Middlesex Univeristy London","RECRUITING","London","NW4 4BT","United Kingdom",{"type":48,"coordinates":49},"Point",[50,51],-0.12574,51.50853,{"lat":51,"lon":50},[54,56,57,59,61],{"name":55,"role":33,"phone":26,"phoneExt":26,"email":35},"Patrycja Brodka Pedro, MSc",{"name":37,"role":33,"phone":26,"phoneExt":26,"email":39},{"name":55,"role":58,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"name":37,"role":60,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"name":62,"role":60,"phone":26,"phoneExt":26,"email":26},"Frank Hills, Professor",{"type":58,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Patrycja Brodka Pedro","PhD Student in Biomedicine, Bioscience Laboratory Technician","100617909",false,"NCT07324746","The Effectiveness of a Herbal Supplement in Osteoarthritis.","Effectiveness of a Herbal Supplement Containing Boswellia Serrata, Curcuma Longa, and Vitis Vinifera in Patients With Osteoarthritis.","Inclusion Criteria:\n\n* Aged ≥ 18\n* Diagnosis of osteoarthritis in knee or hip\n* Numerical Rating Scale (NRS) ≥ 4 during the most painful movement in the last 24 hours\n* Lequesne's Functional Index (LFI) score ≥ 7\n* Ambulant patient\n\nExclusion Criteria:\n\n* Pregnant and breastfeeding\n* Autoimmune disease such as rheumatoid arthritis, gout, lupus\n* Joint trauma, joint injury, joint infection, meniscus tear, complete loss of articular cartilage\n* Expectation of surgery\n* History of the viscous or corticosteroids injections into affected joints or oral corticosteroids within last 12 months\n* Allergy to one of the intervention's ingredients or NSAIDs\n* Peptic ulceration and upper gastrointestinal haemorrhage\n* High alcohol intake, inability to abstain from alcohol, substance abuse, history of addiction\n* Tumor, cancer\n* Abnormal renal or\u002Fand hepatic functions or altered blood chemistry\n* Use of concomitant medication able to interfere with the interventions","ALL","18 Years",{"count":75,"type":76},30,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study aims to evaluate the effectiveness and safety of a combined herbal supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera in adults with clinically diagnosed knee or hip osteoarthritis.\n\nThe primary objective is to determine whether the supplement improves osteoarthritis-related symptoms.\n\nThe supplement will be compared with a placebo.\n\nParticipants will:\n\n* take the supplement and placebo for 4 weeks each, one at a time;\n* complete validated questionnaires (6 times online)\n* perform three performance-based physical tests (6 times online)\n* provide a urine sample",[82,83,84,85],"Osteoarthritis (OA)","Osteoarthritis (OA) of the Hip","Osteoarthritis (OA) of the Knee","Osteoarthritis",[87,88,89,90,85,91,92,93],"Boswellia serrata","Curcuma longa","Curcumin","Turmeric","Grape extract","Knee osteoarthritis","Hip osteoarthritis","2026-01-27",{"date":96,"type":97},"2026-01-29","ACTUAL",{"date":99,"type":97},"2025-12-05",{"date":101,"type":76},"2026-09",{"name":5,"class":6},1]