[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494843":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":27,"locations":35,"responsibleParty":61,"collaborators":63,"id":66,"slug":19,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":19,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":37,"whyStopped":19,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Rhode Island Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Glycemic Load Diet","EXPERIMENTAL","Feeding study with dietary composition (approximately) 50% fat, 20% protein, 30% carbohydrate.",[13],"Behavioral: Low Glycemic Load Diet",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","Food delivery service will provide a low glycemic load diet for 8 weeks, followed by a 4-month period of self-adherence to a low glycemic load diet with close nutritionist follow up",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Kevin J Scully, MB BCh BAO","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":26,"role":23},"Melissa S Putman, MD, MSc","Boston Children's Hospital",[28,32],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},"CONTACT","401-444-5504","kevin_scully@brown.edu",{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},"617-355-7476","melissa.putman@childrens.harvard.edu",[36,50],{"facility":26,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Boston","Massachusetts","02115","United States",{"type":43,"coordinates":44},"Point",[45,46],-71.05977,42.35843,{"lat":46,"lon":45},[49],{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},{"facility":5,"status":37,"city":51,"state":52,"zip":53,"country":41,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Providence","Rhode Island","02903",{"type":43,"coordinates":55},[56,57],-71.41283,41.82399,{"lat":57,"lon":56},[60],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},{"type":62,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[64],{"name":65,"class":6},"Cystic Fibrosis Foundation","100494843",false,"NCT05723445","The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes","DINE","Inclusion Criteria:\n\n* 18 years and above\n* Genetically confirmed diagnosis of CF\n* Diagnosis of pancreatic insufficiency, requiring pancreatic enzyme replacement\n* Criteria for CFRD:\n\nA.) Most recent OGTT 2-hour glucose \\>200 mg\u002FdL within the past two years, and\u002For; B.) HbA1c \\>6.5% in the past two years, and\u002For; C.) Current use of insulin\n\nExclusion Criteria:\n\n* FEV1 \\\u003C50% predicted on most recent pulmonary function testing\n* BMI \\\u003C18 kg\u002Fm2\n* Currently receiving enteral nutrition support via GT feeds\n* Pregnancy, plan to become pregnant in the next 3-months, or sexually active without use of contraception\n* Use of IV antibiotics or systemic supraphysiologic glucocorticoids for CF exacerbation within 1 month\n* Started or stopped treatment with a CFTR modulator within 3 months of enrollment\n* Currently adhering to an LGL or other carbohydrate-restricted diet (carbohydrate intake \\\u003C30% of total daily caloric intake)","ALL","18 Years","70 Years",{"count":76,"type":77},15,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study will evalute the effect of a low glycemic load (LGL diet on dysglycemia, insulin requirements, DXA-derived body composition, gastrointestinal symptoms and quality of life measures in adults with cystic fibrosis-related diabetes (CFRD). We will use continuous glucose monitors (CGM) to assess the LGL diet both in a controlled setting (via a meal delivery company) and in free-living conditions.",[83,84,85],"Cystic Fibrosis","Cystic Fibrosis-related Diabetes","Cystic Fibrosis With Intestinal Manifestations",[87,88,89,90],"Cystic Fibrosis-Related Diabetes","Low Glycemic Load","Continuous Glucose Monitoring","Body Composition","2025-08-16",{"date":93,"type":94},"2025-08-22","ACTUAL",{"date":96,"type":94},"2023-09-01",{"date":98,"type":77},"2026-07-01",{"name":5,"class":6},2]